Clinical characteristics of duodenal-type follicular lymphoma
Abstract Duodenal-Type Follicular Lymphoma (DFL) is a rare extranodular B-cell lymphoma, which mainly involves the duodenum. It typically affects middle-aged individuals and occurs equally in both genders. Common symptoms include upper abdominal discomfort, pain, indigestion, etc. Histopathologicall...
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| Format: | Article |
| Language: | English |
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Springer
2025-07-01
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| Series: | Discover Oncology |
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| Online Access: | https://doi.org/10.1007/s12672-025-02482-7 |
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| author | Lu Wang Wenyan Shen Xiaoyuan Zhang Ling Xue Beili Hu |
| author_facet | Lu Wang Wenyan Shen Xiaoyuan Zhang Ling Xue Beili Hu |
| author_sort | Lu Wang |
| collection | DOAJ |
| description | Abstract Duodenal-Type Follicular Lymphoma (DFL) is a rare extranodular B-cell lymphoma, which mainly involves the duodenum. It typically affects middle-aged individuals and occurs equally in both genders. Common symptoms include upper abdominal discomfort, pain, indigestion, etc. Histopathologically, the condition is characterized by the disruption of follicular architecture, accompanied by the hyperplasia of central cells, and may optionally exhibit the “starry sky” phenomenon. The main treatment for DFL is observation and waiting due to the lack of symptoms and slow progression. The article reviews recent insights into DFL’s epidemiology, symptoms, treatment, and prognosis. |
| format | Article |
| id | doaj-art-d3f75a083ddf410aabf797d2988fad3f |
| institution | Kabale University |
| issn | 2730-6011 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Springer |
| record_format | Article |
| series | Discover Oncology |
| spelling | doaj-art-d3f75a083ddf410aabf797d2988fad3f2025-08-20T04:02:54ZengSpringerDiscover Oncology2730-60112025-07-0116111110.1007/s12672-025-02482-7Clinical characteristics of duodenal-type follicular lymphomaLu Wang0Wenyan Shen1Xiaoyuan Zhang2Ling Xue3Beili Hu4Jiaxing University Master Degree Cultivation Base, Zhejiang Chinese Medical UniversityDepartment of Pathology, The Second Affiliated Hospital of Jiaxing UniversityDepartment of Hematology, The Second Affiliated Hospital of Jiaxing UniversityDepartment of Pathology, The Second Affiliated Hospital of Jiaxing UniversityDepartment of Hematology, The Second Affiliated Hospital of Jiaxing UniversityAbstract Duodenal-Type Follicular Lymphoma (DFL) is a rare extranodular B-cell lymphoma, which mainly involves the duodenum. It typically affects middle-aged individuals and occurs equally in both genders. Common symptoms include upper abdominal discomfort, pain, indigestion, etc. Histopathologically, the condition is characterized by the disruption of follicular architecture, accompanied by the hyperplasia of central cells, and may optionally exhibit the “starry sky” phenomenon. The main treatment for DFL is observation and waiting due to the lack of symptoms and slow progression. The article reviews recent insights into DFL’s epidemiology, symptoms, treatment, and prognosis.https://doi.org/10.1007/s12672-025-02482-7Duodenal follicular lymphomaClinical characteristicsPathological manifestationsTreatment advancesPrognosis |
| spellingShingle | Lu Wang Wenyan Shen Xiaoyuan Zhang Ling Xue Beili Hu Clinical characteristics of duodenal-type follicular lymphoma Discover Oncology Duodenal follicular lymphoma Clinical characteristics Pathological manifestations Treatment advances Prognosis |
| title | Clinical characteristics of duodenal-type follicular lymphoma |
| title_full | Clinical characteristics of duodenal-type follicular lymphoma |
| title_fullStr | Clinical characteristics of duodenal-type follicular lymphoma |
| title_full_unstemmed | Clinical characteristics of duodenal-type follicular lymphoma |
| title_short | Clinical characteristics of duodenal-type follicular lymphoma |
| title_sort | clinical characteristics of duodenal type follicular lymphoma |
| topic | Duodenal follicular lymphoma Clinical characteristics Pathological manifestations Treatment advances Prognosis |
| url | https://doi.org/10.1007/s12672-025-02482-7 |
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