A network-based approach to discover diagnostic metabolite markers associated with depressive features for major depressive disorder

A network-based approach to discover diagnostic metabolite markers associated with depressive features for major depressive disorder

BackgroundDespite the high prevalence of major depressive disorder (MDD), current diagnostic methods rely on subjective clinical assessments, highlighting the need for biomarkers. This study aimed to investigate plasma metabolite signatures in patients with MDD compared with healthy controls (HC) an...

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Bibliographic Details
Main Authors: Yuzhen Zheng, Duan Zeng, Ying Tian, Siyuan Li, Shen He, Huafang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Psychiatry
Subjects:
major depressive disorder
metabolomics
biomarkers
machine-learning
WGCNA
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1610520/full
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