Chi2 weighted ensemble: A multi-layer ensemble approach for skin lesion classification using a novel framework - optimized RegNet synergy with Attention-Triplet.

Skin lesions, including various abnormalities and potentially fatal skin cancers, require early detection for effective treatment. However, current methods often struggle to identify the precise areas responsible for these abnormalities after model dominance dispersion. To address this, we propose a...

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Main Author: Anwar Hossain Efat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0321803
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author Anwar Hossain Efat
author_facet Anwar Hossain Efat
author_sort Anwar Hossain Efat
collection DOAJ
description Skin lesions, including various abnormalities and potentially fatal skin cancers, require early detection for effective treatment. However, current methods often struggle to identify the precise areas responsible for these abnormalities after model dominance dispersion. To address this, we propose a novel Transfer Learning-based framework that integrates Optimized RegNet Synergy architectures and Attention-Triplet mechanisms-comprising channel attention, squeeze-excitation attention, and soft attention-combined with an advanced Ensemble Learning strategy. A significant gap in current research is the lack of techniques for optimal weight allocation in model predictions. Our study fills this gap by introducing the [Formula: see text] Weighted Ensemble (CWE) method, which is further enhanced into a Multi-Layer [Formula: see text] Weighted Ensemble (ML-CWE) to improve model aggregation across multiple layers. Evaluation on the HAM1000 dataset demonstrates that our ML-CWE approach achieves an impressive accuracy of 94.08%, outperforming existing state-of-the-art methods. To enhance model interpretability, we employ Gradient Class Activation Maps (Grad-CAM) to highlight critical regions of interest, improving both transparency and reliability. This work not only boosts accuracy but also facilitates early diagnosis, addressing challenges related to time, accessibility, and cost in skin lesion detection, and offering valuable insights for practical applications in dermatology.
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spelling doaj-art-d3ed0799c0a74d01b453cc01a88270f72025-08-20T01:52:54ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01205e032180310.1371/journal.pone.0321803Chi2 weighted ensemble: A multi-layer ensemble approach for skin lesion classification using a novel framework - optimized RegNet synergy with Attention-Triplet.Anwar Hossain EfatSkin lesions, including various abnormalities and potentially fatal skin cancers, require early detection for effective treatment. However, current methods often struggle to identify the precise areas responsible for these abnormalities after model dominance dispersion. To address this, we propose a novel Transfer Learning-based framework that integrates Optimized RegNet Synergy architectures and Attention-Triplet mechanisms-comprising channel attention, squeeze-excitation attention, and soft attention-combined with an advanced Ensemble Learning strategy. A significant gap in current research is the lack of techniques for optimal weight allocation in model predictions. Our study fills this gap by introducing the [Formula: see text] Weighted Ensemble (CWE) method, which is further enhanced into a Multi-Layer [Formula: see text] Weighted Ensemble (ML-CWE) to improve model aggregation across multiple layers. Evaluation on the HAM1000 dataset demonstrates that our ML-CWE approach achieves an impressive accuracy of 94.08%, outperforming existing state-of-the-art methods. To enhance model interpretability, we employ Gradient Class Activation Maps (Grad-CAM) to highlight critical regions of interest, improving both transparency and reliability. This work not only boosts accuracy but also facilitates early diagnosis, addressing challenges related to time, accessibility, and cost in skin lesion detection, and offering valuable insights for practical applications in dermatology.https://doi.org/10.1371/journal.pone.0321803
spellingShingle Anwar Hossain Efat
Chi2 weighted ensemble: A multi-layer ensemble approach for skin lesion classification using a novel framework - optimized RegNet synergy with Attention-Triplet.
PLoS ONE
title Chi2 weighted ensemble: A multi-layer ensemble approach for skin lesion classification using a novel framework - optimized RegNet synergy with Attention-Triplet.
title_full Chi2 weighted ensemble: A multi-layer ensemble approach for skin lesion classification using a novel framework - optimized RegNet synergy with Attention-Triplet.
title_fullStr Chi2 weighted ensemble: A multi-layer ensemble approach for skin lesion classification using a novel framework - optimized RegNet synergy with Attention-Triplet.
title_full_unstemmed Chi2 weighted ensemble: A multi-layer ensemble approach for skin lesion classification using a novel framework - optimized RegNet synergy with Attention-Triplet.
title_short Chi2 weighted ensemble: A multi-layer ensemble approach for skin lesion classification using a novel framework - optimized RegNet synergy with Attention-Triplet.
title_sort chi2 weighted ensemble a multi layer ensemble approach for skin lesion classification using a novel framework optimized regnet synergy with attention triplet
url https://doi.org/10.1371/journal.pone.0321803
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