Pleural empyema caused by Salmonella enteritidis in a patient with non-Hodgkin lymphoma
Introduction. Extraintestinal manifestations of nontyphoidal salmonellosis are usually seen in patients with cellular immunodeficiency. Pleural empyema caused by nontyphoidal Salmonella is very rare clinical presentation of salmonellosis and there are just a few cases described in a literat...
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2016-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501600004K.pdf |
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| _version_ | 1850173986066923520 |
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| author | Kojić Miroslav Nožić Darko Tarabar Olivera Perišić Nenad |
| author_facet | Kojić Miroslav Nožić Darko Tarabar Olivera Perišić Nenad |
| author_sort | Kojić Miroslav |
| collection | DOAJ |
| description | Introduction. Extraintestinal manifestations of nontyphoidal salmonellosis
are usually seen in patients with cellular immunodeficiency. Pleural empyema
caused by nontyphoidal Salmonella is very rare clinical presentation of
salmonellosis and there are just a few cases described in a literature. We
presented a very rare case of pleural empyema caused by Salmonella
enteritidis in a patient with non-Hodgkin limphoma. Case report. A
60-year-old male with low grade B-cell lymphoma, mucosa associated lymphoid
tissue (MALT) type in IV clinical degree, manifested with infiltration of
stomach, bronchus, pleura and peritoneum was admitted to the hospital.
Initially the patient was presented with non-specific symptoms and signs,
suggesting poor general condition. During the hospitalization his pleural
fluid became purulent and changes in blood counts were registered with the
increase of leukocytes, especially neutrophils. A large number of leukocytes
was found by microscopic evaluation of pleural fluid and Salmonella
enteritidis was isolated by its culture. There were no pathogenic bacteria in
stool culture and hemoculture remained sterile. Toxins A and B of Clostridium
difficile were not detected in stool. The patient was treated by
ciprofloxacin and cefrtiaxone for 14 days with drainage of the purulent
content, what was followed by the resolution and organization of the pleural
fluid. After the stabilization of his general condition, chemotherapy with
cyclophosphamide, vincristine, prednisone (COP) was introduced, with complete
response. Conclusion. Although rare, pleural empyema caused by nontyphoidal
Salmonella should be considered in patients with severe immunosuppression,
because appropriate antimicrobial therapy with surgical measures are very
important for the outcome in these patients. |
| format | Article |
| id | doaj-art-d3ec3ff662364bb280b0aeecf31be699 |
| institution | OA Journals |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-d3ec3ff662364bb280b0aeecf31be6992025-08-20T02:19:45ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202016-01-0173328028310.2298/VSP141031004K0042-84501600004KPleural empyema caused by Salmonella enteritidis in a patient with non-Hodgkin lymphomaKojić Miroslav0Nožić Darko1Tarabar Olivera2Perišić Nenad3Military Medical Academy, Clinic for Infectious and Tropical Diseases, BelgradeMilitary Medical Academy, Clinic for Infectious and Tropical Diseases, Belgrade + University of Defense, Faculty of Medicine of the Military Medical Academy, BelgradeUniversity of Defense, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Clinic for Hematology, BelgradeMilitary Medical Academy, Clinic for Gastroenterology and Hepatology, BelgradeIntroduction. Extraintestinal manifestations of nontyphoidal salmonellosis are usually seen in patients with cellular immunodeficiency. Pleural empyema caused by nontyphoidal Salmonella is very rare clinical presentation of salmonellosis and there are just a few cases described in a literature. We presented a very rare case of pleural empyema caused by Salmonella enteritidis in a patient with non-Hodgkin limphoma. Case report. A 60-year-old male with low grade B-cell lymphoma, mucosa associated lymphoid tissue (MALT) type in IV clinical degree, manifested with infiltration of stomach, bronchus, pleura and peritoneum was admitted to the hospital. Initially the patient was presented with non-specific symptoms and signs, suggesting poor general condition. During the hospitalization his pleural fluid became purulent and changes in blood counts were registered with the increase of leukocytes, especially neutrophils. A large number of leukocytes was found by microscopic evaluation of pleural fluid and Salmonella enteritidis was isolated by its culture. There were no pathogenic bacteria in stool culture and hemoculture remained sterile. Toxins A and B of Clostridium difficile were not detected in stool. The patient was treated by ciprofloxacin and cefrtiaxone for 14 days with drainage of the purulent content, what was followed by the resolution and organization of the pleural fluid. After the stabilization of his general condition, chemotherapy with cyclophosphamide, vincristine, prednisone (COP) was introduced, with complete response. Conclusion. Although rare, pleural empyema caused by nontyphoidal Salmonella should be considered in patients with severe immunosuppression, because appropriate antimicrobial therapy with surgical measures are very important for the outcome in these patients.http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501600004K.pdfempyema, pleuraldiagnosissalmonella enteritidislymphoma, non-Hodgkin |
| spellingShingle | Kojić Miroslav Nožić Darko Tarabar Olivera Perišić Nenad Pleural empyema caused by Salmonella enteritidis in a patient with non-Hodgkin lymphoma Vojnosanitetski Pregled empyema, pleural diagnosis salmonella enteritidis lymphoma, non-Hodgkin |
| title | Pleural empyema caused by Salmonella enteritidis in a patient with non-Hodgkin lymphoma |
| title_full | Pleural empyema caused by Salmonella enteritidis in a patient with non-Hodgkin lymphoma |
| title_fullStr | Pleural empyema caused by Salmonella enteritidis in a patient with non-Hodgkin lymphoma |
| title_full_unstemmed | Pleural empyema caused by Salmonella enteritidis in a patient with non-Hodgkin lymphoma |
| title_short | Pleural empyema caused by Salmonella enteritidis in a patient with non-Hodgkin lymphoma |
| title_sort | pleural empyema caused by salmonella enteritidis in a patient with non hodgkin lymphoma |
| topic | empyema, pleural diagnosis salmonella enteritidis lymphoma, non-Hodgkin |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501600004K.pdf |
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