The potential mechanism of action of gut flora and bile acids through the TGR5/TRPV1 signaling pathway in diabetic peripheral neuropathic pain

The potential mechanism of action of gut flora and bile acids through the TGR5/TRPV1 signaling pathway in diabetic peripheral neuropathic pain

Diabetic peripheral neuropathic pain (DPNP) is a major complication of diabetes that markedly affects the quality of life and health status of patients. Recent studies have investigated the potential regulatory influence of gut flora and bile acids on DPNP via the TGR5/TRPV1 signaling pathway. Dysbi...

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Bibliographic Details
Main Authors: Peng Chen, Xian Jiang, Jia Fu, Cehua Ou, Yao Li, Jing Jia, Changli Liao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Endocrinology
Subjects:
diabetic peripheral neuropathic pain
gut flora
bile acids
TGR5
TRPV1
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1419160/full
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