Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease
This minireview provides current summaries of beta-blocker use in the management of hypertension and/or chronic kidney disease. Accumulated evidence suggests that atenolol is not sufficiently effective as a primary tool to treat hypertension. The less-than-adequate effect of beta-blockers in lowerin...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2014/919256 |
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| _version_ | 1849473227881971712 |
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| author | Hirofumi Tomiyama Akira Yamashina |
| author_facet | Hirofumi Tomiyama Akira Yamashina |
| author_sort | Hirofumi Tomiyama |
| collection | DOAJ |
| description | This minireview provides current summaries of beta-blocker use in the management of hypertension and/or chronic kidney disease. Accumulated evidence suggests that atenolol is not sufficiently effective as a primary tool to treat hypertension. The less-than-adequate effect of beta-blockers in lowering the blood pressure and on vascular protection, and the unfavorable effects of these drugs, as compared to other antihypertensive agents, on the metabolic profile have been pointed out. On the other hand, in patients with chronic kidney disease, renin-angiotensin system blockers are the drugs of first choice for achieving the goal of renal protection. Recent studies have reported that vasodilatory beta-blockers have adequate antihypertensive efficacy and less harmful effects on the metabolic profile, and also exert beneficial effects on endothelial function and renal protection. However, there is still not sufficient evidence on the beneficial effects of the new beta-blockers. |
| format | Article |
| id | doaj-art-d3dff6f8e30c4cd59e3836b52e29d53a |
| institution | Kabale University |
| issn | 2090-0384 2090-0392 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-d3dff6f8e30c4cd59e3836b52e29d53a2025-08-20T03:24:12ZengWileyInternational Journal of Hypertension2090-03842090-03922014-01-01201410.1155/2014/919256919256Beta-Blockers in the Management of Hypertension and/or Chronic Kidney DiseaseHirofumi Tomiyama0Akira Yamashina1Second Department of Internal Medicine, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku-ku, Tokyo 160-0023, JapanSecond Department of Internal Medicine, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku-ku, Tokyo 160-0023, JapanThis minireview provides current summaries of beta-blocker use in the management of hypertension and/or chronic kidney disease. Accumulated evidence suggests that atenolol is not sufficiently effective as a primary tool to treat hypertension. The less-than-adequate effect of beta-blockers in lowering the blood pressure and on vascular protection, and the unfavorable effects of these drugs, as compared to other antihypertensive agents, on the metabolic profile have been pointed out. On the other hand, in patients with chronic kidney disease, renin-angiotensin system blockers are the drugs of first choice for achieving the goal of renal protection. Recent studies have reported that vasodilatory beta-blockers have adequate antihypertensive efficacy and less harmful effects on the metabolic profile, and also exert beneficial effects on endothelial function and renal protection. However, there is still not sufficient evidence on the beneficial effects of the new beta-blockers.http://dx.doi.org/10.1155/2014/919256 |
| spellingShingle | Hirofumi Tomiyama Akira Yamashina Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease International Journal of Hypertension |
| title | Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease |
| title_full | Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease |
| title_fullStr | Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease |
| title_full_unstemmed | Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease |
| title_short | Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease |
| title_sort | beta blockers in the management of hypertension and or chronic kidney disease |
| url | http://dx.doi.org/10.1155/2014/919256 |
| work_keys_str_mv | AT hirofumitomiyama betablockersinthemanagementofhypertensionandorchronickidneydisease AT akirayamashina betablockersinthemanagementofhypertensionandorchronickidneydisease |