Molluscicidal and Schistosomicidal Activities of 2-(1<i>H</i>-Pyrazol-1-<i>yl</i>)-1,3,4-thiadiazole Derivatives

Molluscicidal and Schistosomicidal Activities of 2-(1<i>H</i>-Pyrazol-1-<i>yl</i>)-1,3,4-thiadiazole Derivatives

<b>Background/objectives:</b> Schistosomiasis is caused by flatworms of the genus <i>Schistosoma</i>, for which mollusks of the genus <i>Biomphalaria</i> are intermediate hosts. Niclosamide (NCL) is a molluscicide recommended by the World Health Organization (WHO)...

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Main Authors: Leonardo da Silva Rangel, Daniel Tadeu Gomes Gonzaga, Ana Cláudia Rodrigues da Silva, Natalia Lindmar von Ranke, Carlos Rangel Rodrigues, José Augusto Albuquerque dos Santos, Nubia Boechat, Keyla Nunes Farias Gomes, Guilherme Pegas Teixeira, Robson Xavier Faria
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceuticals
Subjects:
<i>Biomphalaria glabrata</i>
schistosomiasis
1,3,4-thiadiazole
synthetic molecules
Online Access:https://www.mdpi.com/1424-8247/18/3/429
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