Under conditions of high wall shear stress, several PfEBA and PfRH ligands are important for malaria Plasmodium falciparum blood-stage growth

Under conditions of high wall shear stress, several PfEBA and PfRH ligands are important for malaria Plasmodium falciparum blood-stage growth

ABSTRACT Malaria kills over 600,000 people annually, with all clinical symptoms arising from blood-stage infection. Plasmodium falciparum blood-stage replication happens primarily in the blood circulation, bone marrow, and spleen, where there are flow-generated forces, yet most in vitro growth assay...

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Bibliographic Details
Main Authors: Emma Kals, Morten Kals, Pietro Cicuta, Julian C. Rayner
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:mBio
Subjects:
malaria
Plasmodium falciparum
orbital shaker
growth assay
PfEBA
PfRH
Online Access:https://journals.asm.org/doi/10.1128/mbio.01499-25
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