Solubilization of ibuprofen for freeze dried parenteral dosage forms
Ibuprofen, a weakly acidic non-steroidal anti-inflammatory drug having poor aqueous solubility, is a challenging drug for the development of pharmaceutical formulations, resulting in numerous research attempts focusing on improvement of its solubility and consequently bioavailability. Most studies h...
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Main Authors: | Preskar Maja, Vrbanec Tomislav, Vrečer Franc, Šket Primož, Plavec Janez, Gašperlin Mirjana |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2019-03-01
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Series: | Acta Pharmaceutica |
Subjects: | |
Online Access: | https://doi.org/10.2478/acph-2019-0009 |
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