Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel
Abstract Fc‐gamma receptor (FcγR) activation by soluble IgG immune complexes (sICs) represents a major mechanism of inflammation in certain autoimmune diseases such as systemic lupus erythematosus (SLE). A robust and scalable test system allowing for the detection and quantification of sIC bioactivi...
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| Main Authors: | Haizhang Chen, Andrea Maul‐Pavicic, Martin Holzer, Magdalena Huber, Ulrich Salzer, Nina Chevalier, Reinhard E Voll, Hartmut Hengel, Philipp Kolb |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2021-11-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.202114182 |
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