Rare presentation of drug-induced oral erythema multiforme and its management: a case report
Aim. This case report discusses a rare variant of drug-induced erythema multiforme, focusing on its clinical features, diagnosis, and management. Background. Drug-induced erythema multiforme (DI-EM) is a hypersensitivity reaction occurring due to exposure to certain medications. DI-EM typically pres...
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| Format: | Article |
| Language: | English |
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Amaltea Medical Publishing House
2024-06-01
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| Series: | Romanian Journal of Stomatology |
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| Online Access: | https://rjs.com.ro/articles/2024.2/RJS_2024_2_Art-06.pdf |
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| author | Sulaiman S Alqahtani Faris M Alabeedi Meshari M Alwadai Mohammed H Althaiban |
| author_facet | Sulaiman S Alqahtani Faris M Alabeedi Meshari M Alwadai Mohammed H Althaiban |
| author_sort | Sulaiman S Alqahtani |
| collection | DOAJ |
| description | Aim. This case report discusses a rare variant of drug-induced erythema multiforme, focusing on its clinical features, diagnosis, and management. Background. Drug-induced erythema multiforme (DI-EM) is a hypersensitivity reaction occurring due to exposure to certain medications. DI-EM typically presents as erythematous and painful lesions on the oral mucosa, including the lips, tongue, and buccal mucosa. Case description. A 42-year-old male was referred to the Oral Medicine clinic with a chief complaint of painful lip ulceration and eruptions on the body after consuming medications. A detailed history was taken, and after a thorough examination, a perilesional biopsy for histopathological and immunopathological tests was performed. Following the exclusion of all other conditions with a similar presentation, a diagnosis of drug-induced erythema multiforme (DI-EM) was established. Conclusion. DI-EM can pose a diagnostic challenge due to its presentation. However, a diagnosis can be established by excluding other conditions associated with chronic inflammation or the formation of vesicles or bullae. Clinical Significance. DI-EM is a rare variant of EM with a very low prevalence in the general population, making it a challenging condition to diagnose due to its similarity in presentation with other mucocutaneous disorders. A thorough medical history, along with histopathology and immunology tests, coupled with ruling out other diseases and noting a positive history of recent drug consumption, aids in recognizing this condition, given the absence of any confirmatory diagnostic test. Early diagnosis and cessation of causative drugs, along with supportive medications, contribute to the complete resolution of the condition. |
| format | Article |
| id | doaj-art-d3c00ede3b1c4683a0523c17d3011200 |
| institution | Kabale University |
| issn | 1843-0805 2069-6078 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Stomatology |
| spelling | doaj-art-d3c00ede3b1c4683a0523c17d30112002025-01-08T08:00:16ZengAmaltea Medical Publishing HouseRomanian Journal of Stomatology1843-08052069-60782024-06-0170218318810.37897/RJS.2024.2.6Rare presentation of drug-induced oral erythema multiforme and its management: a case reportSulaiman S Alqahtani0Faris M Alabeedi1Meshari M Alwadai2Mohammed H Althaiban3Department of Oral & Maxillofacial Surgery and Diagnostic Sciences, Faculty of Dentistry, Najran University, Najran, Saudi ArabiaDepartment of Oral & Maxillofacial Surgery and Diagnostic Sciences, Faculty of Dentistry, Najran University, Najran, Saudi ArabiaFaculty of Dentistry, Najran University, Najran, Saudi ArabiaFaculty of Dentistry, Najran University, Najran, Saudi ArabiaAim. This case report discusses a rare variant of drug-induced erythema multiforme, focusing on its clinical features, diagnosis, and management. Background. Drug-induced erythema multiforme (DI-EM) is a hypersensitivity reaction occurring due to exposure to certain medications. DI-EM typically presents as erythematous and painful lesions on the oral mucosa, including the lips, tongue, and buccal mucosa. Case description. A 42-year-old male was referred to the Oral Medicine clinic with a chief complaint of painful lip ulceration and eruptions on the body after consuming medications. A detailed history was taken, and after a thorough examination, a perilesional biopsy for histopathological and immunopathological tests was performed. Following the exclusion of all other conditions with a similar presentation, a diagnosis of drug-induced erythema multiforme (DI-EM) was established. Conclusion. DI-EM can pose a diagnostic challenge due to its presentation. However, a diagnosis can be established by excluding other conditions associated with chronic inflammation or the formation of vesicles or bullae. Clinical Significance. DI-EM is a rare variant of EM with a very low prevalence in the general population, making it a challenging condition to diagnose due to its similarity in presentation with other mucocutaneous disorders. A thorough medical history, along with histopathology and immunology tests, coupled with ruling out other diseases and noting a positive history of recent drug consumption, aids in recognizing this condition, given the absence of any confirmatory diagnostic test. Early diagnosis and cessation of causative drugs, along with supportive medications, contribute to the complete resolution of the condition.https://rjs.com.ro/articles/2024.2/RJS_2024_2_Art-06.pdfdrug-induced erythema multiformeem diagnosisem variantsherpes associated erythema multiforme |
| spellingShingle | Sulaiman S Alqahtani Faris M Alabeedi Meshari M Alwadai Mohammed H Althaiban Rare presentation of drug-induced oral erythema multiforme and its management: a case report Romanian Journal of Stomatology drug-induced erythema multiforme em diagnosis em variants herpes associated erythema multiforme |
| title | Rare presentation of drug-induced oral erythema multiforme and its management: a case report |
| title_full | Rare presentation of drug-induced oral erythema multiforme and its management: a case report |
| title_fullStr | Rare presentation of drug-induced oral erythema multiforme and its management: a case report |
| title_full_unstemmed | Rare presentation of drug-induced oral erythema multiforme and its management: a case report |
| title_short | Rare presentation of drug-induced oral erythema multiforme and its management: a case report |
| title_sort | rare presentation of drug induced oral erythema multiforme and its management a case report |
| topic | drug-induced erythema multiforme em diagnosis em variants herpes associated erythema multiforme |
| url | https://rjs.com.ro/articles/2024.2/RJS_2024_2_Art-06.pdf |
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