A Rare Case Report of Amiodarone-Induced Bone Marrow Granuloma
Amiodarone has rarely been reported to induce bone marrow granulomas. In this case, we describe the case of a 67-year-old man who was incidentally found to have pancytopenia while receiving amiodarone therapy for 18 months. A bone marrow biopsy revealed noncaseating granulomas, presumably causing pa...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American College of Physicians
2024-08-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2024.0026 |
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| Summary: | Amiodarone has rarely been reported to induce bone marrow granulomas. In this case, we describe the case of a 67-year-old man who was incidentally found to have pancytopenia while receiving amiodarone therapy for 18 months. A bone marrow biopsy revealed noncaseating granulomas, presumably causing pancytopenia. Subsequently, amiodarone was withdrawn, resulting in a gradual improvement of the pancytopenia. The resolution of amiodarone-induced bone marrow granuloma and associated cytopenia is readily achievable through physicians’ awareness and appropriate discontinuation of the medication therapy. Consequently, we recommend considering amiodarone as a potential contributor to bone marrow granuloma and cytopenia. |
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| ISSN: | 2767-7664 |