Prediction of hemorrhagic complications during treatment of children with malignant diseases

Achievement of platelet diagnostic threshold less than 28.0 × 109/l and prothrombin activity less than 40 % with system inflammatory response (SIRS) were considered as high risk for spontaneous bleeding complication development within the next day in cancer patients. If platelets count is more than...

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Main Authors: V. V. Dmitriev, I. A. Dunaev
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Онкогематология
Subjects:
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/65
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author V. V. Dmitriev
I. A. Dunaev
author_facet V. V. Dmitriev
I. A. Dunaev
author_sort V. V. Dmitriev
collection DOAJ
description Achievement of platelet diagnostic threshold less than 28.0 × 109/l and prothrombin activity less than 40 % with system inflammatory response (SIRS) were considered as high risk for spontaneous bleeding complication development within the next day in cancer patients. If platelets count is more than 28.5 × 109/l in a combination to prothrombin activity ≥ 40 % and absence of SIRS, it is possible to say that coagulations changes cannot be the independent cause of bleeding and does not require correction of coagulation parameters.
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spelling doaj-art-d3ab609ba40e4497bba2241a4a8db7b12025-08-20T03:01:30ZrusABV-pressОнкогематология1818-83462413-40232014-07-0171152110.17650/1818-8346-2012-7-1-15-2180Prediction of hemorrhagic complications during treatment of children with malignant diseasesV. V. Dmitriev0I. A. Dunaev1Belarusian Research Center for Pediatric Oncology and HematologyBelarusian Research Center for Pediatric Oncology and HematologyAchievement of platelet diagnostic threshold less than 28.0 × 109/l and prothrombin activity less than 40 % with system inflammatory response (SIRS) were considered as high risk for spontaneous bleeding complication development within the next day in cancer patients. If platelets count is more than 28.5 × 109/l in a combination to prothrombin activity ≥ 40 % and absence of SIRS, it is possible to say that coagulations changes cannot be the independent cause of bleeding and does not require correction of coagulation parameters.https://oncohematology.abvpress.ru/ongm/article/view/65acute leukemiamalignant diseaseschildrencoagulation disordersbleeding prognosis
spellingShingle V. V. Dmitriev
I. A. Dunaev
Prediction of hemorrhagic complications during treatment of children with malignant diseases
Онкогематология
acute leukemia
malignant diseases
children
coagulation disorders
bleeding prognosis
title Prediction of hemorrhagic complications during treatment of children with malignant diseases
title_full Prediction of hemorrhagic complications during treatment of children with malignant diseases
title_fullStr Prediction of hemorrhagic complications during treatment of children with malignant diseases
title_full_unstemmed Prediction of hemorrhagic complications during treatment of children with malignant diseases
title_short Prediction of hemorrhagic complications during treatment of children with malignant diseases
title_sort prediction of hemorrhagic complications during treatment of children with malignant diseases
topic acute leukemia
malignant diseases
children
coagulation disorders
bleeding prognosis
url https://oncohematology.abvpress.ru/ongm/article/view/65
work_keys_str_mv AT vvdmitriev predictionofhemorrhagiccomplicationsduringtreatmentofchildrenwithmalignantdiseases
AT iadunaev predictionofhemorrhagiccomplicationsduringtreatmentofchildrenwithmalignantdiseases