Sensitivity of Self-reported Opium Use in Cancer Patients: Implications for conducting epidemiological studies
Background: Underreporting bias related to opium use is a significant methodological issue that can threaten the results of epidemiologic studies, particularly when opium use is the exposure of interest. In our current study, we aimed to measure the sensitivity of opium use. among cancer patients a...
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| Format: | Article |
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Tehran University of Medical Sciences
2024-11-01
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| Series: | Basic & Clinical Cancer Research |
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| Online Access: | https://bccr.tums.ac.ir/index.php/bccrj/article/view/529 |
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| author | Vahideh Mohseni Maryam Hadji Mina Khaki Omid Nabavian Kazem Zendehdel Hamideh Rashidian |
| author_facet | Vahideh Mohseni Maryam Hadji Mina Khaki Omid Nabavian Kazem Zendehdel Hamideh Rashidian |
| author_sort | Vahideh Mohseni |
| collection | DOAJ |
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Background: Underreporting bias related to opium use is a significant methodological issue that can threaten the results of epidemiologic studies, particularly when opium use is the exposure of interest. In our current study, we aimed to measure the sensitivity of opium use. among cancer patients and identify the contributing factors
Method: In a cross-sectional study, we examined the sensitivity of self-reported opium use among cancer cases. In this study, we avoided using urine tests as the gold standard to prevent false positive results, given that most cancer patients use opioids to alleviate their pain. Instead, we relied on their reports of use to anesthesiologists as the gold standard and compared it with their reports to interviewers to calculate sensitivity
Results: The sensitivity of self-reported opium use among cancer patients was approximately 63.33% (95% CI: 43.86% – 80.07%). Interestingly, this sensitivity was significantly higher among cigarette users 88.24% (95% CI: 63.56% – 98.54%) compared to non-users 30.77% (95% CI: 9.09% – 61.43%). Additionally, the sensitivity of self-reported opium use was higher among alcohol users and participants with low socioeconomic status compared to their counterparts, although these differences were not statistically significant.
Conclusion: The observed sensitivity of self-reported opium use among cancer patients underscores the importance of meticulous and comprehensive approaches for collecting and interpreting self-reported substance use data. Researchers and policymakers should consider contributing factors to the sensitivity of self-reported opium use.
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| format | Article |
| id | doaj-art-d3ab15cd530a4592a1252f0358afd0f5 |
| institution | Kabale University |
| issn | 2228-6527 2228-5466 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Basic & Clinical Cancer Research |
| spelling | doaj-art-d3ab15cd530a4592a1252f0358afd0f52025-02-09T08:54:18ZengTehran University of Medical SciencesBasic & Clinical Cancer Research2228-65272228-54662024-11-01154Sensitivity of Self-reported Opium Use in Cancer Patients: Implications for conducting epidemiological studiesVahideh Mohseni0Maryam Hadji1Mina Khaki2Omid Nabavian3Kazem Zendehdel4Hamideh Rashidian1- Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, IranHealth Sciences Unit, Faculty of Social Sciences, Tampere University, Tampere, FinlandCancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, IranDepartment of Anesthesiology, Imam Hospital Complex, School of Medicine, Tehran University of Medical Sciences, Tehran, IranDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy Background: Underreporting bias related to opium use is a significant methodological issue that can threaten the results of epidemiologic studies, particularly when opium use is the exposure of interest. In our current study, we aimed to measure the sensitivity of opium use. among cancer patients and identify the contributing factors Method: In a cross-sectional study, we examined the sensitivity of self-reported opium use among cancer cases. In this study, we avoided using urine tests as the gold standard to prevent false positive results, given that most cancer patients use opioids to alleviate their pain. Instead, we relied on their reports of use to anesthesiologists as the gold standard and compared it with their reports to interviewers to calculate sensitivity Results: The sensitivity of self-reported opium use among cancer patients was approximately 63.33% (95% CI: 43.86% – 80.07%). Interestingly, this sensitivity was significantly higher among cigarette users 88.24% (95% CI: 63.56% – 98.54%) compared to non-users 30.77% (95% CI: 9.09% – 61.43%). Additionally, the sensitivity of self-reported opium use was higher among alcohol users and participants with low socioeconomic status compared to their counterparts, although these differences were not statistically significant. Conclusion: The observed sensitivity of self-reported opium use among cancer patients underscores the importance of meticulous and comprehensive approaches for collecting and interpreting self-reported substance use data. Researchers and policymakers should consider contributing factors to the sensitivity of self-reported opium use. https://bccr.tums.ac.ir/index.php/bccrj/article/view/529Self-reportedSensitivityOpiumCancer |
| spellingShingle | Vahideh Mohseni Maryam Hadji Mina Khaki Omid Nabavian Kazem Zendehdel Hamideh Rashidian Sensitivity of Self-reported Opium Use in Cancer Patients: Implications for conducting epidemiological studies Basic & Clinical Cancer Research Self-reported Sensitivity Opium Cancer |
| title | Sensitivity of Self-reported Opium Use in Cancer Patients: Implications for conducting epidemiological studies |
| title_full | Sensitivity of Self-reported Opium Use in Cancer Patients: Implications for conducting epidemiological studies |
| title_fullStr | Sensitivity of Self-reported Opium Use in Cancer Patients: Implications for conducting epidemiological studies |
| title_full_unstemmed | Sensitivity of Self-reported Opium Use in Cancer Patients: Implications for conducting epidemiological studies |
| title_short | Sensitivity of Self-reported Opium Use in Cancer Patients: Implications for conducting epidemiological studies |
| title_sort | sensitivity of self reported opium use in cancer patients implications for conducting epidemiological studies |
| topic | Self-reported Sensitivity Opium Cancer |
| url | https://bccr.tums.ac.ir/index.php/bccrj/article/view/529 |
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