Prediction of the effect of the photodynamic therapy on survival in patients with stage IV of pancreatic cancer

The article presents the results of a study of survival after complex palliative treatment of patients with malignant tumors of the pancreas stage IV in two comparable groups of patients. The aim of the study is to determine the prognostic factors affecting survival in patients with stage IV pancrea...

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Main Authors: A. Е. Tseimakh, S. G. Shtofin, V. А. Kurtukov, V. N. Teplukhin, Ia. N. Shoykhet, M. E. Tseimakh
Format: Article
Language:Russian
Published: Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" 2023-01-01
Series:Biomedical Photonics
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Online Access:https://www.pdt-journal.com/jour/article/view/565
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author A. Е. Tseimakh
S. G. Shtofin
V. А. Kurtukov
V. N. Teplukhin
Ia. N. Shoykhet
M. E. Tseimakh
author_facet A. Е. Tseimakh
S. G. Shtofin
V. А. Kurtukov
V. N. Teplukhin
Ia. N. Shoykhet
M. E. Tseimakh
author_sort A. Е. Tseimakh
collection DOAJ
description The article presents the results of a study of survival after complex palliative treatment of patients with malignant tumors of the pancreas stage IV in two comparable groups of patients. The aim of the study is to determine the prognostic factors affecting survival in patients with stage IV pancreatic cancer who received local and systemic photodynamic therapy. In the main group, which consisted of 19 patients with histologically veried stage IV pancreatic maligant tumor, palliative treatment was performed using photodynamic therapy. In the comparison group, consisting of 28 patients with histologically veried malignant tumor of the pancreas stage IV, palliative treatment was performed without the use of photodynamic therapy. On the background of the use of local and systemic photodynamic therapy in the main group it was observed a statistically significant increase in life expectancy compared with the comparison group. The three-month survival of patients who received local and systemic photodynamic therapy is affected by the level of brinogen before treatment. The level of brinogen above 3.4 g/l makes it possible to predict a decrease in the probability of three-month survival after photodynamic therapy. Thus, complex treatment with the use of photodynamic therapy for stage IV malignant tumors of the pancreas can increase the survival rate of patients.
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id doaj-art-d393a0b8f4ae47409a93f2bded7972b5
institution DOAJ
issn 2413-9432
language Russian
publishDate 2023-01-01
publisher Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"
record_format Article
series Biomedical Photonics
spelling doaj-art-d393a0b8f4ae47409a93f2bded7972b52025-08-20T03:00:54ZrusNon-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"Biomedical Photonics2413-94322023-01-01114253110.24931/2413-9432-2022-11-4-25-31265Prediction of the effect of the photodynamic therapy on survival in patients with stage IV of pancreatic cancerA. Е. Tseimakh0S. G. Shtofin1V. А. Kurtukov2V. N. Teplukhin3Ia. N. Shoykhet4M. E. Tseimakh5Altai State Medical UniversityNovosibirsk State Medical UniversityNovosibirsk State Medical UniversityState hospital №5Altai State Medical UniversityAltai State Medical UniversityThe article presents the results of a study of survival after complex palliative treatment of patients with malignant tumors of the pancreas stage IV in two comparable groups of patients. The aim of the study is to determine the prognostic factors affecting survival in patients with stage IV pancreatic cancer who received local and systemic photodynamic therapy. In the main group, which consisted of 19 patients with histologically veried stage IV pancreatic maligant tumor, palliative treatment was performed using photodynamic therapy. In the comparison group, consisting of 28 patients with histologically veried malignant tumor of the pancreas stage IV, palliative treatment was performed without the use of photodynamic therapy. On the background of the use of local and systemic photodynamic therapy in the main group it was observed a statistically significant increase in life expectancy compared with the comparison group. The three-month survival of patients who received local and systemic photodynamic therapy is affected by the level of brinogen before treatment. The level of brinogen above 3.4 g/l makes it possible to predict a decrease in the probability of three-month survival after photodynamic therapy. Thus, complex treatment with the use of photodynamic therapy for stage IV malignant tumors of the pancreas can increase the survival rate of patients.https://www.pdt-journal.com/jour/article/view/565malignant tumors of the pancreasphotodynamic therapyforecastingsurvivalprognostic factors
spellingShingle A. Е. Tseimakh
S. G. Shtofin
V. А. Kurtukov
V. N. Teplukhin
Ia. N. Shoykhet
M. E. Tseimakh
Prediction of the effect of the photodynamic therapy on survival in patients with stage IV of pancreatic cancer
Biomedical Photonics
malignant tumors of the pancreas
photodynamic therapy
forecasting
survival
prognostic factors
title Prediction of the effect of the photodynamic therapy on survival in patients with stage IV of pancreatic cancer
title_full Prediction of the effect of the photodynamic therapy on survival in patients with stage IV of pancreatic cancer
title_fullStr Prediction of the effect of the photodynamic therapy on survival in patients with stage IV of pancreatic cancer
title_full_unstemmed Prediction of the effect of the photodynamic therapy on survival in patients with stage IV of pancreatic cancer
title_short Prediction of the effect of the photodynamic therapy on survival in patients with stage IV of pancreatic cancer
title_sort prediction of the effect of the photodynamic therapy on survival in patients with stage iv of pancreatic cancer
topic malignant tumors of the pancreas
photodynamic therapy
forecasting
survival
prognostic factors
url https://www.pdt-journal.com/jour/article/view/565
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AT vnteplukhin predictionoftheeffectofthephotodynamictherapyonsurvivalinpatientswithstageivofpancreaticcancer
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