Introduction to the forensic research via omics markers in environmental health vulnerable areas (FROM) study
This research group (forensic research via omics markers in environmental health vulnerable areas: FROM) aimed to develop biomarkers for exposure to environmental hazards and diseases, assess environmental diseases, and apply and verify these biomarkers in environmentally vulnerable areas. Environme...
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| Format: | Article |
| Language: | English |
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Korean Society of Epidemiology
2024-07-01
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| Series: | Epidemiology and Health |
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| Online Access: | http://www.e-epih.org/upload/pdf/epih-46-e2024062.pdf |
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| author | Jung-Yeon Kwon Woo Jin Kim Yong Min Cho Byoung-Gwon Kim Seungho Lee Jee Hyun Rho Sang-Yong Eom Dahee Han Kyung-Hwa Choi Jang-Hee Lee Jeeyoung Kim Sungho Won Hee-Gyoo Kang Sora Mun Hyun Ju Yoo Jung-Woong Kim Kwan Lee Won-Ju Park Seongchul Hong Young-Seoub Hong |
| author_facet | Jung-Yeon Kwon Woo Jin Kim Yong Min Cho Byoung-Gwon Kim Seungho Lee Jee Hyun Rho Sang-Yong Eom Dahee Han Kyung-Hwa Choi Jang-Hee Lee Jeeyoung Kim Sungho Won Hee-Gyoo Kang Sora Mun Hyun Ju Yoo Jung-Woong Kim Kwan Lee Won-Ju Park Seongchul Hong Young-Seoub Hong |
| author_sort | Jung-Yeon Kwon |
| collection | DOAJ |
| description | This research group (forensic research via omics markers in environmental health vulnerable areas: FROM) aimed to develop biomarkers for exposure to environmental hazards and diseases, assess environmental diseases, and apply and verify these biomarkers in environmentally vulnerable areas. Environmentally vulnerable areas—including refineries, abandoned metal mines, coal-fired power plants, waste incinerators, cement factories, and areas with high exposure to particulate matter—along with control areas, were selected for epidemiological investigations. A total of 1,157 adults, who had resided in these areas for over 10 years, were recruited between June 2021 and September 2023. Personal characteristics of the study participants were gathered through a survey. Biological samples, specifically blood and urine, were collected during the field investigations, separated under refrigerated conditions, and then transported to the laboratory for biomarker analysis. Analyses of heavy metals, environmental hazards, and adducts were conducted on these blood and urine samples. Additionally, omics analyses of epigenomes, proteomes, and metabolomes were performed using the blood samples. The biomarkers identified in this study will be utilized to assess the risk of environmental disease occurrence and to evaluate the impact on the health of residents in environmentally vulnerable areas, following the validation of diagnostic accuracy for these diseases. |
| format | Article |
| id | doaj-art-d39268ce67034969945ecedbf0d747ed |
| institution | DOAJ |
| issn | 2092-7193 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Korean Society of Epidemiology |
| record_format | Article |
| series | Epidemiology and Health |
| spelling | doaj-art-d39268ce67034969945ecedbf0d747ed2025-08-20T03:12:36ZengKorean Society of EpidemiologyEpidemiology and Health2092-71932024-07-014610.4178/epih.e20240621528Introduction to the forensic research via omics markers in environmental health vulnerable areas (FROM) studyJung-Yeon Kwon0Woo Jin Kim1Yong Min Cho2Byoung-Gwon Kim3Seungho Lee4Jee Hyun Rho5Sang-Yong Eom6Dahee Han7Kyung-Hwa Choi8Jang-Hee Lee9Jeeyoung Kim10Sungho Won11Hee-Gyoo Kang12Sora Mun13Hyun Ju Yoo14Jung-Woong Kim15Kwan Lee16Won-Ju Park17Seongchul Hong18Young-Seoub Hong19 Department of Preventive Medicine, Dong-A University College of Medicine, Busan, Korea Department of Internal Medicine and Environmental Health Center, Kangwon National University, Chuncheon, Korea Department of Nano, Chemical & Biological Engineering, Seokyeong University, Seoul, Korea Department of Preventive Medicine, Dong-A University College of Medicine, Busan, Korea Department of Preventive Medicine, Dong-A University College of Medicine, Busan, Korea Department of Preventive Medicine, Dong-A University College of Medicine, Busan, Korea Department of Preventive Medicine, Chungbuk National University College of Medicine, Cheongju, Korea Department of Nano, Chemical & Biological Engineering, Seokyeong University, Seoul, Korea Department of Preventive Medicine, Dankook University College of Medicine, Cheonan, Korea SD Medical Research Institute, Yongin, Korea Department of Internal Medicine and Environmental Health Center, Kangwon National University, Chuncheon, Korea Department of Public Health Sciences, Seoul National University, Seoul, Korea Department of Biomedical Laboratory Science, Eulji University College of Health Sciences, Seongnam, Korea Department of Biomedical Laboratory Science, Eulji University College of Health Sciences, Seongnam, Korea Department of Convergence Medicine, Department of Digital Medicine, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Department of Life Sciences, Chung-Ang University, Seoul, Korea Department of Preventive Medicine, Dongguk University College of Medicine, Gyeongju, Korea Department of Occupational and Environmental Medicine, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Hwasun, Korea Department of Preventive Medicine, Jeju National University College of Medicine, Jeju, Korea Department of Preventive Medicine, Dong-A University College of Medicine, Busan, KoreaThis research group (forensic research via omics markers in environmental health vulnerable areas: FROM) aimed to develop biomarkers for exposure to environmental hazards and diseases, assess environmental diseases, and apply and verify these biomarkers in environmentally vulnerable areas. Environmentally vulnerable areas—including refineries, abandoned metal mines, coal-fired power plants, waste incinerators, cement factories, and areas with high exposure to particulate matter—along with control areas, were selected for epidemiological investigations. A total of 1,157 adults, who had resided in these areas for over 10 years, were recruited between June 2021 and September 2023. Personal characteristics of the study participants were gathered through a survey. Biological samples, specifically blood and urine, were collected during the field investigations, separated under refrigerated conditions, and then transported to the laboratory for biomarker analysis. Analyses of heavy metals, environmental hazards, and adducts were conducted on these blood and urine samples. Additionally, omics analyses of epigenomes, proteomes, and metabolomes were performed using the blood samples. The biomarkers identified in this study will be utilized to assess the risk of environmental disease occurrence and to evaluate the impact on the health of residents in environmentally vulnerable areas, following the validation of diagnostic accuracy for these diseases.http://www.e-epih.org/upload/pdf/epih-46-e2024062.pdfenvironmentmultiomicsbiomarkers |
| spellingShingle | Jung-Yeon Kwon Woo Jin Kim Yong Min Cho Byoung-Gwon Kim Seungho Lee Jee Hyun Rho Sang-Yong Eom Dahee Han Kyung-Hwa Choi Jang-Hee Lee Jeeyoung Kim Sungho Won Hee-Gyoo Kang Sora Mun Hyun Ju Yoo Jung-Woong Kim Kwan Lee Won-Ju Park Seongchul Hong Young-Seoub Hong Introduction to the forensic research via omics markers in environmental health vulnerable areas (FROM) study Epidemiology and Health environment multiomics biomarkers |
| title | Introduction to the forensic research via omics markers in environmental health vulnerable areas (FROM) study |
| title_full | Introduction to the forensic research via omics markers in environmental health vulnerable areas (FROM) study |
| title_fullStr | Introduction to the forensic research via omics markers in environmental health vulnerable areas (FROM) study |
| title_full_unstemmed | Introduction to the forensic research via omics markers in environmental health vulnerable areas (FROM) study |
| title_short | Introduction to the forensic research via omics markers in environmental health vulnerable areas (FROM) study |
| title_sort | introduction to the forensic research via omics markers in environmental health vulnerable areas from study |
| topic | environment multiomics biomarkers |
| url | http://www.e-epih.org/upload/pdf/epih-46-e2024062.pdf |
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