Vitamin D supplementation in a post-pandemic era: A narrative review
Vitamin D is a fat-soluble molecule referring to the different isoforms, ergocalciferol (D2) and cholecalciferol (D3). Its physiological functions include increasing calcium serum concentrations. 25-hydroxyvitamin D3 (25(OH)D) (Calcifediol), a non-active, circulating instant precursor is seen as a p...
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| Format: | Article |
| Language: | English |
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AOSIS
2023-10-01
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| Series: | South African Family Practice |
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| Online Access: | https://safpj.co.za/index.php/safpj/article/view/5752 |
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| author | Pheagane G. Bopape Chrisna Wagenaar Madan Poka Elmien Bronkhorst |
| author_facet | Pheagane G. Bopape Chrisna Wagenaar Madan Poka Elmien Bronkhorst |
| author_sort | Pheagane G. Bopape |
| collection | DOAJ |
| description | Vitamin D is a fat-soluble molecule referring to the different isoforms, ergocalciferol (D2) and cholecalciferol (D3). Its physiological functions include increasing calcium serum concentrations. 25-hydroxyvitamin D3 (25(OH)D) (Calcifediol), a non-active, circulating instant precursor is seen as a pre-hormone. Studies have shown that a deficiency in calcifediol is related to chronic conditions such as cardiovascular, musculoskeletal, immune system, neurological, and anti-neoplastic functions. Vitamin D supplementation has shown its benefit as prophylaxis and treatment during the coronavirus disease 2019 (COVID-19) pandemic and an increase in the prescribing of vitamin D supplementation has been observed. The intention of this review article is to provide guidance on the recommended dosage regimen as a prophylactic measure during COVID-19 and its use as a supplement in general. From this review article, it is clear that vitamin D has an important role to play not only in COVID-19 but also in various other health aspects of the human body.
Contribution: This review article highlighted the role of vitamin D in managing vitamin D deficiency and its role as a supplement in the management of respiratory tract infections, especially COVID-19. This overview can assist physicians in optimising healthcare by optimised dosing recommendations and indications. |
| format | Article |
| id | doaj-art-d38c35d5f03d45b8bfe5f866fc026e51 |
| institution | Kabale University |
| issn | 2078-6190 2078-6204 |
| language | English |
| publishDate | 2023-10-01 |
| publisher | AOSIS |
| record_format | Article |
| series | South African Family Practice |
| spelling | doaj-art-d38c35d5f03d45b8bfe5f866fc026e512025-08-20T03:43:57ZengAOSISSouth African Family Practice2078-61902078-62042023-10-01651e1e610.4102/safp.v65i1.57524357Vitamin D supplementation in a post-pandemic era: A narrative reviewPheagane G. Bopape0Chrisna Wagenaar1Madan Poka2Elmien Bronkhorst3Department of Clinical Pharmacy, Faculty of Health Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, PretoriaDepartment of Clinical Pharmacy, Faculty of Health Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, PretoriaDepartment of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, PretoriaDepartment of Clinical Pharmacy, Faculty of Health Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, PretoriaVitamin D is a fat-soluble molecule referring to the different isoforms, ergocalciferol (D2) and cholecalciferol (D3). Its physiological functions include increasing calcium serum concentrations. 25-hydroxyvitamin D3 (25(OH)D) (Calcifediol), a non-active, circulating instant precursor is seen as a pre-hormone. Studies have shown that a deficiency in calcifediol is related to chronic conditions such as cardiovascular, musculoskeletal, immune system, neurological, and anti-neoplastic functions. Vitamin D supplementation has shown its benefit as prophylaxis and treatment during the coronavirus disease 2019 (COVID-19) pandemic and an increase in the prescribing of vitamin D supplementation has been observed. The intention of this review article is to provide guidance on the recommended dosage regimen as a prophylactic measure during COVID-19 and its use as a supplement in general. From this review article, it is clear that vitamin D has an important role to play not only in COVID-19 but also in various other health aspects of the human body. Contribution: This review article highlighted the role of vitamin D in managing vitamin D deficiency and its role as a supplement in the management of respiratory tract infections, especially COVID-19. This overview can assist physicians in optimising healthcare by optimised dosing recommendations and indications.https://safpj.co.za/index.php/safpj/article/view/5752vitamin dcovid-19chronic diseasesdeficiencycalcifediolcholecalciferol |
| spellingShingle | Pheagane G. Bopape Chrisna Wagenaar Madan Poka Elmien Bronkhorst Vitamin D supplementation in a post-pandemic era: A narrative review South African Family Practice vitamin d covid-19 chronic diseases deficiency calcifediol cholecalciferol |
| title | Vitamin D supplementation in a post-pandemic era: A narrative review |
| title_full | Vitamin D supplementation in a post-pandemic era: A narrative review |
| title_fullStr | Vitamin D supplementation in a post-pandemic era: A narrative review |
| title_full_unstemmed | Vitamin D supplementation in a post-pandemic era: A narrative review |
| title_short | Vitamin D supplementation in a post-pandemic era: A narrative review |
| title_sort | vitamin d supplementation in a post pandemic era a narrative review |
| topic | vitamin d covid-19 chronic diseases deficiency calcifediol cholecalciferol |
| url | https://safpj.co.za/index.php/safpj/article/view/5752 |
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