Ocular Melanoma Metastasizing to Intra-Abdominal Lymph Nodes

Background. Visceral metastatic spread of ocular melanoma most commonly occurs via hematogenous route to the liver. Lymphatic spread of ocular melanoma into abdominal lymph nodes has not been reported previously. Case Presentation. A 47-year-old man with a history of ocular melanoma presented with a...

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Main Authors: David Aranovich, Karen Meir, Michal M. Lotem, Liat Appelbaum, Hadar Merhav
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2013/534730
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author David Aranovich
Karen Meir
Michal M. Lotem
Liat Appelbaum
Hadar Merhav
author_facet David Aranovich
Karen Meir
Michal M. Lotem
Liat Appelbaum
Hadar Merhav
author_sort David Aranovich
collection DOAJ
description Background. Visceral metastatic spread of ocular melanoma most commonly occurs via hematogenous route to the liver. Lymphatic spread of ocular melanoma into abdominal lymph nodes has not been reported previously. Case Presentation. A 47-year-old man with a history of ocular melanoma presented with a soft tissue mass on CT scan. The mass encased the portal structures of the hepaticoduodenal ligament. Image-guided biopsy revealed it to be a metastatic melanoma to lymph nodes. The patient underwent surgery with the intent to prolong disease-free survival. On final pathological examination, two lymph nodes were found harboring metastatic melanoma. Conclusion. Extrahepatic lymphatic intra-abdominal spread of ocular melanoma is not impossible. Since this mode of spread is rare, the oncologic significance of surgical resection of isolated intra-abdominal nodal with metastatic ocular melanoma is difficult to determine at the present time.
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spelling doaj-art-d38c224214d24e008cf704879f0a50262025-02-03T05:59:52ZengWileyCase Reports in Surgery2090-69002090-69192013-01-01201310.1155/2013/534730534730Ocular Melanoma Metastasizing to Intra-Abdominal Lymph NodesDavid Aranovich0Karen Meir1Michal M. Lotem2Liat Appelbaum3Hadar Merhav4Department of Surgery, Rabin Medical Center, Beilinson Hospital, 39 Jabotinsky Street, 49100 Petah Tikva, IsraelDepartment of Pathology, Hadassah University Hospital, Ein Kerm, P.O. Box 1200, 91120 Jerusalem, IsraelCenter for Melanoma and Cancer Immunotherapy Sharett Institute of Oncology, Hadassah University Hospital, Ein Kerm, P.O. Box 1200, 91120 Jerusalem, IsraelDepartment of Diagnostic Radiology, Hadassah University Hospital, Ein Kerm, P.O. Box 1200, 91120 Jerusalem, IsraelDepartment of Surgery, Hadassah University Hospital, Ein Kerm, P.O. Box 1200, 91120 Jerusalem, IsraelBackground. Visceral metastatic spread of ocular melanoma most commonly occurs via hematogenous route to the liver. Lymphatic spread of ocular melanoma into abdominal lymph nodes has not been reported previously. Case Presentation. A 47-year-old man with a history of ocular melanoma presented with a soft tissue mass on CT scan. The mass encased the portal structures of the hepaticoduodenal ligament. Image-guided biopsy revealed it to be a metastatic melanoma to lymph nodes. The patient underwent surgery with the intent to prolong disease-free survival. On final pathological examination, two lymph nodes were found harboring metastatic melanoma. Conclusion. Extrahepatic lymphatic intra-abdominal spread of ocular melanoma is not impossible. Since this mode of spread is rare, the oncologic significance of surgical resection of isolated intra-abdominal nodal with metastatic ocular melanoma is difficult to determine at the present time.http://dx.doi.org/10.1155/2013/534730
spellingShingle David Aranovich
Karen Meir
Michal M. Lotem
Liat Appelbaum
Hadar Merhav
Ocular Melanoma Metastasizing to Intra-Abdominal Lymph Nodes
Case Reports in Surgery
title Ocular Melanoma Metastasizing to Intra-Abdominal Lymph Nodes
title_full Ocular Melanoma Metastasizing to Intra-Abdominal Lymph Nodes
title_fullStr Ocular Melanoma Metastasizing to Intra-Abdominal Lymph Nodes
title_full_unstemmed Ocular Melanoma Metastasizing to Intra-Abdominal Lymph Nodes
title_short Ocular Melanoma Metastasizing to Intra-Abdominal Lymph Nodes
title_sort ocular melanoma metastasizing to intra abdominal lymph nodes
url http://dx.doi.org/10.1155/2013/534730
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AT karenmeir ocularmelanomametastasizingtointraabdominallymphnodes
AT michalmlotem ocularmelanomametastasizingtointraabdominallymphnodes
AT liatappelbaum ocularmelanomametastasizingtointraabdominallymphnodes
AT hadarmerhav ocularmelanomametastasizingtointraabdominallymphnodes