В6.А-DYSFPRMD/GENEJ MICE AS A GENETIC MODEL OF DYSFERLINOPATHY

В6.А-DYSFPRMD/GENEJ MICE AS A GENETIC MODEL OF DYSFERLINOPATHY

The aim of the work was behavioral and pathomorphological phenotyping of the mice knockout for the DYSF gene, which plays an important role in the development and progression of dysferlinopathy.Materials and methods. A B6.A-Dysfprmd/GeneJ (Bla/J) mice subline was used in the work. During the study,...

Full description

Saved in:

Bibliographic Details
Main Authors:	M. V. Korokin, E. V. Kuzubova, A. I. Radchenko, R. V. Deev, I. A. Yakovlev, A. V. Deikin, N. S. Zhunusov, A. M. Krayushkina, V. M. Pokrovsky, O. A. Puchenkova, K. D. Chaprov, N. V. Ekimova, S. N. Bardakov, O. N. Chernova, A. M. Emelin, I. S. Limaev
Format:	Article
Language:	Russian
Published:	Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute 2022-12-01
Series:	Фармация и фармакология (Пятигорск)
Subjects:	dysferlinopathy dysf gene myoshi’s myopathy muscular dystrophy phenotyping knockout genotyping animals mouse model b6.a-dysfprmd/genej
Online Access:	https://www.pharmpharm.ru/jour/article/view/1200
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Reasons for misdiagnosis of polymyositis in patients with dysferlinopathy: a clinical case
by: S. N. Bardakov, et al.
Published: (2022-12-01)

Muscle MRI Pattern in Dysferlinopathy and its Correlation with Dysferlin Gait
by: Tanushree Chawla, et al.
Published: (2025-03-01)

Rapid Quantitative Assessment of Muscle Sodium Dynamics After Exercise Using 23Na‐MRI in Dysferlinopathy and Healthy Controls
by: Mary A. Neal, et al.
Published: (2025-02-01)

Miyoshi myopathy: diagnosis of a familial case of dysferlinopathy
by: V. P. Fedotov, et al.
Published: (2016-03-01)

Genetic and phenotypic characteristics of 3 patients with limb-girdle muscular dystrophy: experience in a medical center in Mexico
by: Valentina Martínez-Montoya, et al.
Published: (2025-03-01)

CONVENTIONAL APPROACHES TO THE THERAPY OF HEREDITARY MYOPATHIES
by: M. V. Pokrovsky, et al.
Published: (2022-12-01)

Myositis mimics
by: Sujata Ganguly, et al.
Published: (2021-01-01)

DEVELOPMENT OF MURINE STEM CELLS WITH CONDITIONAL KNOCKOUT OF HUMANIZED SNCA GENE
by: E. A. Patrakhanov, et al.
Published: (2023-02-01)

A new mutation in the TYMP-gene: clinical and morphological characteristics of a patient with MNGIE syndrome
by: S. N. Bardakov, et al.
Published: (2022-12-01)

Dysferlinopathy as cause of long-term hyperCKemia with preserved strength
by: Ikreet Cheema, et al.
Published: (2025-06-01)

STUDY OF THE PHARMACOLOGICAL ACTIVITY OF NOVEL EPOR/CD131 HETERORECEPTOR AGONISTS IN MICE WITH ENDOTHELIAL-SPECIFIC EXPRESSION OF MUTANT POLG GENE
by: М. В. Korokin, et al.
Published: (2021-09-01)

Marching neuropathy of the nervus digitalis plantaris proprii medialis halluci among military personnel
by: S. N. Bardakov, et al.
Published: (2023-06-01)

Isolation, identification and quantification of flavonoids from the flowers of <i>Staphylea pinnata</i> L.
by: A. Y. Sokolova, et al.
Published: (2024-06-01)

Current understanding of the rational diagnostics and treatment of acquired myasthenia gravis. Part 2: treatment
by: S. N. Bardakov, et al.
Published: (2016-09-01)

Current aspects of the clinic, diagnosis and treatment of acquired myasthenia gravis (review). Part 1: diagnostics
by: S. N. Bardakov, et al.
Published: (2016-06-01)

Study of acute toxicity, endothelial- and cardioprotective properties of phenolic and thiophenolic derivatives of 2H-imidazoles
by: O. A. Puchenkova, et al.
Published: (2025-07-01)

11-amino acid peptide imitating the structure of erythropoietin α-helix b improves endothelial function, but stimulates thrombosis in rats.
by: M. V. Korokin, et al.
Published: (2020-01-01)

Contents of plasmin, α1-antitrypsin and α2-macroglobulin in blood of patients with cerebral infarction and discircular encephalopathy before the treatment
by: N. A. Kuznetsova, et al.
Published: (2004-09-01)

PHARMACOLOGICAL CORRECTION OF THE PURULENT PROCESS OF WOUND BY PHYTOMINERALSORBENTUM IN RATS
by: U. A. KRUT, et al.
Published: (2017-06-01)

Phenotypic heterogeneity and diagnostic features of transthyretin amyloidosis with polyneuropathy
by: S. S. Nikitin, et al.
Published: (2021-12-01)

Perspectives and commitments of smart education in Russia
by: A. V. Bodyako, et al.
Published: (2022-06-01)

Effect of the recombinant chymosins of different origins on production process of soft cheese
by: D. S. Myagkonosov, et al.
Published: (2022-07-01)

Influence of different milk-clotting enzymes on the process of producing soft cheeses
by: D. S. Myagkonosov, et al.
Published: (2021-10-01)

Therapeutic apheresis in the complex pathogenetic therapy of anti-NMDA encephalitis associated with ovarian teratoma at a late stage of the disease
by: S. N. Bardakov, et al.
Published: (2021-12-01)

Genetic determinants of myocardial electric instability in patients with coronary heart disease undergoing endovascular intervention
by: Yu. I. Afanasiev, et al.
Published: (1970-01-01)

MORPHOLOGY OF LYMPH NODES IN THE EXPERIMENT (AGE-RELATED AND CIRCANNUAL ASPECTS)
by: I. I. Markov, et al.
Published: (2020-11-01)

Whole Exome Sequencing Identified a Stop-Gained Mutation in DYSF Gene Associated With Dysferlinopathy in an Iranian Family
by: Saba Baghshomali, et al.
Published: (2025-01-01)

Whole Exome Sequencing Leading to the Diagnosis of Dysferlinopathy with a Novel Missense Mutation (c.959G>C)
by: Abhisek Swaika, et al.
Published: (2016-01-01)

Antisense oligonucleotide-mediated exon 27 skipping restores dysferlin function in dysferlinopathy patient-derived muscle cells
by: Naoki Suzuki
Published: (2025-03-01)

Programmed immunoadsorption with regeneration of adsoption columns in the treatment of lupus nephritis
by: A. A. Sokolov, et al.
Published: (2020-09-01)

THE CLINICAL CASE OF THYMECTOMY USING COMBINED APPROACHES
by: I. I. Dzidzava, et al.
Published: (2019-12-01)

The effect of prolonged oxygen therapy on the clinical course of the disease and diaphragm function in patients with chronic obstructive pulmonary disease and hypoxemic respiratory failure (three-year follow-up)
by: O. N. Titova, et al.
Published: (2019-10-01)

EFFECT OF FUROSTANOL GLYCOSIDES FROM CULTURED DIOSCOREA DELTOIDEA CELLS ON REGULATORY FUNCTION OF ENDOTHELIUM IN A RAT MODEL OF HYPOESTROGEN-INDUCED ENDOTHELIAL DYSFUNCTION
by: E. B. Artyushkova, et al.
Published: (2016-01-01)

TRANSFORMING GROWTH FACTOR Β IN BLOOD SERUM AND BRONCHOALVEOLAR LAVAGE FLUID IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE
by: E. A. Surkova, et al.
Published: (2014-07-01)

Protective role of 3-oxypyridine derivatives in rats’ steroid-induced osteoporosis associated with reduced oxidative stress and recovery of nitric oxide formation
by: A. P. Danilenko, et al.
Published: (2023-05-01)

Determining horizontal well profile with side branches to ensure target operating parameters
by: L. G. Korshunova, et al.
Published: (2022-05-01)

Mozart effect in patients with epilepsy
by: Ya. B. Skiba, et al.
Published: (2021-10-01)

Features of remodeling of right heart chambers according to tissue Doppler and its correlation with cardiac rhythm disturbance in patients with COPD 2-3 severity
by: O. A. Zhuk, et al.
Published: (2014-09-01)

A ROLE OF ANGIOTENSIN-CONVERTING ENZYME IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE SUMMARY
by: N. D. Elshin, et al.
Published: (2017-09-01)

Expression of GR, COX2и MMP1 genes in peripheral blood leukocytes after intensive therapy of the patients with chronic obstructive lung disease
by: N. D. Yelshin, et al.
Published: (2015-03-01)