Decoding the "Pain-to-Door" interval using psychological, medical, and demographic factors: A multi-center study.
<h4>Background</h4>Reducing the amount of time between the onset of symptoms and presentation to a healthcare facility, namely the "pain-to-door" interval, is of utmost importance in patients with myocardial infarction. In the present study, we aimed to shed light on the psycho...
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| Format: | Article |
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Public Library of Science (PLoS)
2025-01-01
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| Online Access: | https://doi.org/10.1371/journal.pone.0325140 |
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| author | Hamidreza Roohafza Feridoun Noohi Sara Bagherieh Marjan Mansourian Media Babahajiani Hamidreza Marateb Mohammadjavad Alemzadeh Ansari Aboozar Fakhr Mousavi Mohammad Mehdi Peighambari Masoumeh Sadeghi |
| author_facet | Hamidreza Roohafza Feridoun Noohi Sara Bagherieh Marjan Mansourian Media Babahajiani Hamidreza Marateb Mohammadjavad Alemzadeh Ansari Aboozar Fakhr Mousavi Mohammad Mehdi Peighambari Masoumeh Sadeghi |
| author_sort | Hamidreza Roohafza |
| collection | DOAJ |
| description | <h4>Background</h4>Reducing the amount of time between the onset of symptoms and presentation to a healthcare facility, namely the "pain-to-door" interval, is of utmost importance in patients with myocardial infarction. In the present study, we aimed to shed light on the psychological, medical, and demographic factors that are associated with this vital time, and the details of this association.<h4>Methods</h4>We used the baseline data of 1685 participants from a 3-year, multi-centric, cohort study. The pain to door time was estimated as the interval between symptoms' onset and arrival at the hospital. Patients were asked to fill out valid and reliable questionnaires regarding sociodemographic factors, depression, health anxiety, type D personality, sense of coherence, coping strategies, and quality of life. Data was then analyzed to attain the p-value and hazard ratios (HR) of different variables.<h4>Results</h4>In the multivariate analysis, being male (HR: 0.81, 95% CI: 0.68-0.98) and a history of angina (0.82, 0.69-0.96) were associated with shorter pain-to-door durations. A history of diabetes mellitus also made the cut marginally (p-value: 0.059). On the contrary, health anxiety (1.27, 1.09-1.49), history of depression (1.57, 1.21-2.05), high socioeconomic status (1.25, 1.03-1.51) and sense of coherence (1.34, 1.14-1.57) scores were associated with longer pain-to-door durations.<h4>Conclusion</h4>Our findings demonstrate that personal, social, and economical characteristics play a pivotal role in determining patients' pain-to-door time duration. Screening high-risk individuals in terms of the factors that tend to increase the pain-to-door time alongside educating people and healthcare providers on the importance of this interval and its contributing factors must be a priority considering the devastating burden of CVDs. |
| format | Article |
| id | doaj-art-d3899cb603874a838c6301c4affcabba |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
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| spelling | doaj-art-d3899cb603874a838c6301c4affcabba2025-08-20T03:50:06ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01206e032514010.1371/journal.pone.0325140Decoding the "Pain-to-Door" interval using psychological, medical, and demographic factors: A multi-center study.Hamidreza RoohafzaFeridoun NoohiSara BagheriehMarjan MansourianMedia BabahajianiHamidreza MaratebMohammadjavad Alemzadeh AnsariAboozar Fakhr MousaviMohammad Mehdi PeighambariMasoumeh Sadeghi<h4>Background</h4>Reducing the amount of time between the onset of symptoms and presentation to a healthcare facility, namely the "pain-to-door" interval, is of utmost importance in patients with myocardial infarction. In the present study, we aimed to shed light on the psychological, medical, and demographic factors that are associated with this vital time, and the details of this association.<h4>Methods</h4>We used the baseline data of 1685 participants from a 3-year, multi-centric, cohort study. The pain to door time was estimated as the interval between symptoms' onset and arrival at the hospital. Patients were asked to fill out valid and reliable questionnaires regarding sociodemographic factors, depression, health anxiety, type D personality, sense of coherence, coping strategies, and quality of life. Data was then analyzed to attain the p-value and hazard ratios (HR) of different variables.<h4>Results</h4>In the multivariate analysis, being male (HR: 0.81, 95% CI: 0.68-0.98) and a history of angina (0.82, 0.69-0.96) were associated with shorter pain-to-door durations. A history of diabetes mellitus also made the cut marginally (p-value: 0.059). On the contrary, health anxiety (1.27, 1.09-1.49), history of depression (1.57, 1.21-2.05), high socioeconomic status (1.25, 1.03-1.51) and sense of coherence (1.34, 1.14-1.57) scores were associated with longer pain-to-door durations.<h4>Conclusion</h4>Our findings demonstrate that personal, social, and economical characteristics play a pivotal role in determining patients' pain-to-door time duration. Screening high-risk individuals in terms of the factors that tend to increase the pain-to-door time alongside educating people and healthcare providers on the importance of this interval and its contributing factors must be a priority considering the devastating burden of CVDs.https://doi.org/10.1371/journal.pone.0325140 |
| spellingShingle | Hamidreza Roohafza Feridoun Noohi Sara Bagherieh Marjan Mansourian Media Babahajiani Hamidreza Marateb Mohammadjavad Alemzadeh Ansari Aboozar Fakhr Mousavi Mohammad Mehdi Peighambari Masoumeh Sadeghi Decoding the "Pain-to-Door" interval using psychological, medical, and demographic factors: A multi-center study. PLoS ONE |
| title | Decoding the "Pain-to-Door" interval using psychological, medical, and demographic factors: A multi-center study. |
| title_full | Decoding the "Pain-to-Door" interval using psychological, medical, and demographic factors: A multi-center study. |
| title_fullStr | Decoding the "Pain-to-Door" interval using psychological, medical, and demographic factors: A multi-center study. |
| title_full_unstemmed | Decoding the "Pain-to-Door" interval using psychological, medical, and demographic factors: A multi-center study. |
| title_short | Decoding the "Pain-to-Door" interval using psychological, medical, and demographic factors: A multi-center study. |
| title_sort | decoding the pain to door interval using psychological medical and demographic factors a multi center study |
| url | https://doi.org/10.1371/journal.pone.0325140 |
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