Chromatin licensing and DNA replication factor 1 as a potential prognostic and diagnostic biomarker for gastric cancer

Chromatin licensing and DNA replication factor 1 as a potential prognostic and diagnostic biomarker for gastric cancer

Abstract Accurate and timely genetic material replication is essential for preserving genomic integrity. The replication process begins with chromatin licensing and DNA replication factor 1 (CDT1). It has been demonstrated that dysregulated CDT1 expression causes genomic instability, damages DNA, an...

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Bibliographic Details
Main Authors: Sijia Wang, Min Cui, Na Zhou, Meichen Tong, Shuhua Wu, Hong Li, Zhang Cao
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Gastric cancer
CDT1
Proliferation
Invasion
EMT
Online Access:https://doi.org/10.1038/s41598-024-81977-9
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