5-Hydroxytryptophan artificial synaptic vesicles across the blood-brain barrier for the rapid-acting treatment of depressive disorder

5-Hydroxytryptophan artificial synaptic vesicles across the blood-brain barrier for the rapid-acting treatment of depressive disorder

Conventional antidepressants are slow to work and have serious side effects and poor response rates. As a precursor to 5-hydroxytryptamine (5-HT), 5-hydroxytryptophan (5-HTP) can be safely increased in concentration and rapidly metabolized into 5-HT in the brain, but the effectiveness of 5-HTP is se...

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Bibliographic Details
Main Authors: Peng Chang, Jingwen Ma, Ke Li, Wei Wang, Dan Chen, Zhe Liu, Wenhua Zhan, Yun Zeng, Yonghua Zhan
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Materials Today Bio
Subjects:
Depression
5-HTP
Vesicles
Blood-brain barrier
Photothermal-triggered
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424004186
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