Retrospective histomorphological analysis of bone and soft tissue tumors and tumor-like lesions over 32 years in a tertiary healthcare facility
Aims: Clinicopathological features of bone and soft tissue tumors/tumor-like lesions have been shown to vary geographically. This study aims to analyze the clinicopathological features of bone and soft tissue lesions in Ilorin, including both neoplastic and non-neoplastic diseases derived from mesen...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2025-06-01
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| Series: | Gülhane Tıp Dergisi |
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| Online Access: | https://gulhanemedj.org/articles/retrospective-histomorphological-analysis-of-bone-and-soft-tissue-tumors-and-tumor-like-lesions-over-32-years-in-a-tertiary-healthcare-facility/doi/gulhane.galenos.2025.86619 |
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| author | Mumini Wemimo Rasheed Uchechukwu Brian Eziagu Adebayo Ayoade Adekunle Najeem Adedamola Idowu Ismail Salisu Abdullahi Abba Habib Enoch Abiodun Afolayan |
| author_facet | Mumini Wemimo Rasheed Uchechukwu Brian Eziagu Adebayo Ayoade Adekunle Najeem Adedamola Idowu Ismail Salisu Abdullahi Abba Habib Enoch Abiodun Afolayan |
| author_sort | Mumini Wemimo Rasheed |
| collection | DOAJ |
| description | Aims: Clinicopathological features of bone and soft tissue tumors/tumor-like lesions have been shown to vary geographically. This study aims to analyze the clinicopathological features of bone and soft tissue lesions in Ilorin, including both neoplastic and non-neoplastic diseases derived from mesenchymal cells, thus addressing a notable data gap.
Methods: We retrospectively reviewed histopathologically diagnosed cases of bone and soft tissue lesions over thirty-two years (1985 to 2016) at the University of Ilorin Teaching Hospital, Ilorin, Nigeria. Data were extracted from pathology reports and case files.
Results: A total of 970 cases of bone and soft tissue lesions were recorded. The age distribution of the study group ranged from 0 to 81 years with a mean age of 34.5±0.5 years and the male-to-female ratio was 1:1. The lesions of adipose tissue origin constituted the most common (38.4%; 373/969) followed by blood vessels (20.6%; 200/969) and fibrous tissue lesions (18.8%; 182/969) among others. The majority of these bone and soft tissue lesions were benign 80.4%. The most common soft tissue neoplasm was lipoma (32.1%; 311/970). Fibrosarcoma was the most common malignant soft tissue neoplasm (7.8%; 76/970).
Conclusions: Adipocytic tumors were the most prevalent soft tissue lesions, with lipoma being the most frequent specific lesion. Fibrosarcoma was the predominant malignant soft tissue neoplasm, while giant cell tumor was the most commonly diagnosed bone neoplasm. Clinically, these findings highlight the necessity for heightened vigilance and tailored diagnostic strategies for these prevalent tumors in healthcare settings. |
| format | Article |
| id | doaj-art-d379e07e853e49d5977d1f6abcd20d83 |
| institution | Kabale University |
| issn | 2146-8052 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Gülhane Tıp Dergisi |
| spelling | doaj-art-d379e07e853e49d5977d1f6abcd20d832025-08-20T03:44:47ZengGalenos Publishing HouseGülhane Tıp Dergisi2146-80522025-06-01672859310.4274/gulhane.galenos.2025.86619Retrospective histomorphological analysis of bone and soft tissue tumors and tumor-like lesions over 32 years in a tertiary healthcare facilityMumini Wemimo Rasheed0https://orcid.org/0000-0003-4888-6325Uchechukwu Brian Eziagu1https://orcid.org/0000-0003-3951-4976Adebayo Ayoade Adekunle2https://orcid.org/0000-0002-0362-2441Najeem Adedamola Idowu3https://orcid.org/0000-0003-4231-7703Ismail Salisu4https://orcid.org/0000-0001-5857-9105Abdullahi Abba Habib5https://orcid.org/0009-0003-7853-2648Enoch Abiodun Afolayan6https://orcid.org/0000-0002-9728-0664University of Ilorin Teaching Hospital, Department of Anatomic Pathology, Ilorin, NigeriaUniversity of Uyo Teaching Hospital, Department of Histopathology, Uyo, NigeriaLadoke Akıntola University of Technology, Department of Morbid Anatomy and Histopathology, Ogbomoso, NigeriaLadoke Akıntola University of Technology, Department of Surgery, Ogbomoso, NigeriaFederal University Dutse Faculty of Basic Clinical Sciences, Department of Surgery, Dutse, NigeriaFederal University Dutse Faculty of Clinical Sciences, Department of Obstetrics and Gynaecology, Dutse, NigeriaUniversity of Ilorin Teaching Hospital, Department of Anatomic Pathology, Ilorin, NigeriaAims: Clinicopathological features of bone and soft tissue tumors/tumor-like lesions have been shown to vary geographically. This study aims to analyze the clinicopathological features of bone and soft tissue lesions in Ilorin, including both neoplastic and non-neoplastic diseases derived from mesenchymal cells, thus addressing a notable data gap. Methods: We retrospectively reviewed histopathologically diagnosed cases of bone and soft tissue lesions over thirty-two years (1985 to 2016) at the University of Ilorin Teaching Hospital, Ilorin, Nigeria. Data were extracted from pathology reports and case files. Results: A total of 970 cases of bone and soft tissue lesions were recorded. The age distribution of the study group ranged from 0 to 81 years with a mean age of 34.5±0.5 years and the male-to-female ratio was 1:1. The lesions of adipose tissue origin constituted the most common (38.4%; 373/969) followed by blood vessels (20.6%; 200/969) and fibrous tissue lesions (18.8%; 182/969) among others. The majority of these bone and soft tissue lesions were benign 80.4%. The most common soft tissue neoplasm was lipoma (32.1%; 311/970). Fibrosarcoma was the most common malignant soft tissue neoplasm (7.8%; 76/970). Conclusions: Adipocytic tumors were the most prevalent soft tissue lesions, with lipoma being the most frequent specific lesion. Fibrosarcoma was the predominant malignant soft tissue neoplasm, while giant cell tumor was the most commonly diagnosed bone neoplasm. Clinically, these findings highlight the necessity for heightened vigilance and tailored diagnostic strategies for these prevalent tumors in healthcare settings.https://gulhanemedj.org/articles/retrospective-histomorphological-analysis-of-bone-and-soft-tissue-tumors-and-tumor-like-lesions-over-32-years-in-a-tertiary-healthcare-facility/doi/gulhane.galenos.2025.86619lesionsclinicopathologicallipomafibrosarcomailorinnigeria |
| spellingShingle | Mumini Wemimo Rasheed Uchechukwu Brian Eziagu Adebayo Ayoade Adekunle Najeem Adedamola Idowu Ismail Salisu Abdullahi Abba Habib Enoch Abiodun Afolayan Retrospective histomorphological analysis of bone and soft tissue tumors and tumor-like lesions over 32 years in a tertiary healthcare facility Gülhane Tıp Dergisi lesions clinicopathological lipoma fibrosarcoma ilorin nigeria |
| title | Retrospective histomorphological analysis of bone and soft tissue tumors and tumor-like lesions over 32 years in a tertiary healthcare facility |
| title_full | Retrospective histomorphological analysis of bone and soft tissue tumors and tumor-like lesions over 32 years in a tertiary healthcare facility |
| title_fullStr | Retrospective histomorphological analysis of bone and soft tissue tumors and tumor-like lesions over 32 years in a tertiary healthcare facility |
| title_full_unstemmed | Retrospective histomorphological analysis of bone and soft tissue tumors and tumor-like lesions over 32 years in a tertiary healthcare facility |
| title_short | Retrospective histomorphological analysis of bone and soft tissue tumors and tumor-like lesions over 32 years in a tertiary healthcare facility |
| title_sort | retrospective histomorphological analysis of bone and soft tissue tumors and tumor like lesions over 32 years in a tertiary healthcare facility |
| topic | lesions clinicopathological lipoma fibrosarcoma ilorin nigeria |
| url | https://gulhanemedj.org/articles/retrospective-histomorphological-analysis-of-bone-and-soft-tissue-tumors-and-tumor-like-lesions-over-32-years-in-a-tertiary-healthcare-facility/doi/gulhane.galenos.2025.86619 |
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