The mediating and joint effects of depression in the association between cardiovascular health and frailty in middle-aged and elderly people: evidence from NHANES

The mediating and joint effects of depression in the association between cardiovascular health and frailty in middle-aged and elderly people: evidence from NHANES

ObjectiveThis study investigates the correlation between Life’s Essential 8 (LE8), a cardiovascular health (CVH) metric, and frailty in middle-aged and elderly individuals in the United States, also examining how depression mediates this relationship.MethodsParticipants from the NHANES 2005-2018 wer...

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Bibliographic Details
Main Authors: Qiaoli Ma, Zhijuan Zou, Yanpeng Liu, Lei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Psychiatry
Subjects:
Life’s Essential 8
frailty
depression
NHANES
CVH
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1578743/full
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