Lutetium Copper@Hexagonal Boron Nitride Nanocomposite Electrode System for Sensing and Signalling Ciprofloxacin
Abstract Herein, a new electrochemical sensing system based on lutetium copper nanoparticles supported on hexagonal boron nitride (Lu‐Cu@h‐BN) was designed for the sensitive detection of ciprofloxacin (CIP) antibiotic. A simple hydrothermal method was used to synthesize the nanocomposite. The struct...
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Wiley-VCH
2024-07-01
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| Series: | ChemElectroChem |
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| Online Access: | https://doi.org/10.1002/celc.202400168 |
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| author | Collen Nepfumbada Prof. Bhekie B. Mamba Prof. Bart M. Bartlett Prof. Jorge F. Fernández‐Sánchez Prof. Usisipho Feleni |
| author_facet | Collen Nepfumbada Prof. Bhekie B. Mamba Prof. Bart M. Bartlett Prof. Jorge F. Fernández‐Sánchez Prof. Usisipho Feleni |
| author_sort | Collen Nepfumbada |
| collection | DOAJ |
| description | Abstract Herein, a new electrochemical sensing system based on lutetium copper nanoparticles supported on hexagonal boron nitride (Lu‐Cu@h‐BN) was designed for the sensitive detection of ciprofloxacin (CIP) antibiotic. A simple hydrothermal method was used to synthesize the nanocomposite. The structural and morphological characteristics of the as‐prepared nanocomposite were investigated using various analytical techniques such as Fourier transform infrared spectroscopy (FTIR), X‐ray diffraction (XRD), scanning electron microscopy (SEM), and X‐ray photoelectron spectroscopy (XPS). The newly developed Lu‐Cu@h‐BN nanocomposite was used as an electrode modifier for sensing and signalling of CIP. Cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were used to study the electrochemical activities of the bare GCE, Cu‐h‐BN/GCE, Lu‐h‐BN/GCE, Lu‐Cu/GCE, and Lu‐Cu@h‐BN/GCE. The electro‐oxidation of CIP on electrode surface exhibited an irreversible, diffusion‐controlled process. The sensor system obtained a wider linear range of (0.05–100 μM) with a lower detection limit value of 0.03 μM and sensitivity 0.7443 μA μM−1 cm−2. Furthermore, the sensor demonstrated an excellent selectivity, good stability, and reproducibility, with acceptable recoveries of 96 % to 104 % in real water sample analysis. |
| format | Article |
| id | doaj-art-d36d96aa4ae84afc82bbad2d03e3fdd6 |
| institution | Kabale University |
| issn | 2196-0216 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Wiley-VCH |
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| series | ChemElectroChem |
| spelling | doaj-art-d36d96aa4ae84afc82bbad2d03e3fdd62025-08-20T03:47:36ZengWiley-VCHChemElectroChem2196-02162024-07-011114n/an/a10.1002/celc.202400168Lutetium Copper@Hexagonal Boron Nitride Nanocomposite Electrode System for Sensing and Signalling CiprofloxacinCollen Nepfumbada0Prof. Bhekie B. Mamba1Prof. Bart M. Bartlett2Prof. Jorge F. Fernández‐Sánchez3Prof. Usisipho Feleni4Institute for nanotechnology and water sustainability (iNanoWS)) College of Science Engineering and Technology (CSET) University of South Africa (UNISA) Florida campus 1709 Johannesburg South AfricaInstitute for nanotechnology and water sustainability (iNanoWS)) College of Science Engineering and Technology (CSET) University of South Africa (UNISA) Florida campus 1709 Johannesburg South AfricaInstitute for nanotechnology and water sustainability (iNanoWS)) College of Science Engineering and Technology (CSET) University of South Africa (UNISA) Florida campus 1709 Johannesburg South AfricaDepartment of Analytical Chemistry University of Granada 18071 Granada SpainInstitute for nanotechnology and water sustainability (iNanoWS)) College of Science Engineering and Technology (CSET) University of South Africa (UNISA) Florida campus 1709 Johannesburg South AfricaAbstract Herein, a new electrochemical sensing system based on lutetium copper nanoparticles supported on hexagonal boron nitride (Lu‐Cu@h‐BN) was designed for the sensitive detection of ciprofloxacin (CIP) antibiotic. A simple hydrothermal method was used to synthesize the nanocomposite. The structural and morphological characteristics of the as‐prepared nanocomposite were investigated using various analytical techniques such as Fourier transform infrared spectroscopy (FTIR), X‐ray diffraction (XRD), scanning electron microscopy (SEM), and X‐ray photoelectron spectroscopy (XPS). The newly developed Lu‐Cu@h‐BN nanocomposite was used as an electrode modifier for sensing and signalling of CIP. Cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were used to study the electrochemical activities of the bare GCE, Cu‐h‐BN/GCE, Lu‐h‐BN/GCE, Lu‐Cu/GCE, and Lu‐Cu@h‐BN/GCE. The electro‐oxidation of CIP on electrode surface exhibited an irreversible, diffusion‐controlled process. The sensor system obtained a wider linear range of (0.05–100 μM) with a lower detection limit value of 0.03 μM and sensitivity 0.7443 μA μM−1 cm−2. Furthermore, the sensor demonstrated an excellent selectivity, good stability, and reproducibility, with acceptable recoveries of 96 % to 104 % in real water sample analysis.https://doi.org/10.1002/celc.202400168Ciprofloxacindetectionelectrochemical sensorhydrothermal methodnanocomposite |
| spellingShingle | Collen Nepfumbada Prof. Bhekie B. Mamba Prof. Bart M. Bartlett Prof. Jorge F. Fernández‐Sánchez Prof. Usisipho Feleni Lutetium Copper@Hexagonal Boron Nitride Nanocomposite Electrode System for Sensing and Signalling Ciprofloxacin ChemElectroChem Ciprofloxacin detection electrochemical sensor hydrothermal method nanocomposite |
| title | Lutetium Copper@Hexagonal Boron Nitride Nanocomposite Electrode System for Sensing and Signalling Ciprofloxacin |
| title_full | Lutetium Copper@Hexagonal Boron Nitride Nanocomposite Electrode System for Sensing and Signalling Ciprofloxacin |
| title_fullStr | Lutetium Copper@Hexagonal Boron Nitride Nanocomposite Electrode System for Sensing and Signalling Ciprofloxacin |
| title_full_unstemmed | Lutetium Copper@Hexagonal Boron Nitride Nanocomposite Electrode System for Sensing and Signalling Ciprofloxacin |
| title_short | Lutetium Copper@Hexagonal Boron Nitride Nanocomposite Electrode System for Sensing and Signalling Ciprofloxacin |
| title_sort | lutetium copper hexagonal boron nitride nanocomposite electrode system for sensing and signalling ciprofloxacin |
| topic | Ciprofloxacin detection electrochemical sensor hydrothermal method nanocomposite |
| url | https://doi.org/10.1002/celc.202400168 |
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