Short-term effects of Ahmed valve implantation on ocular biometry and corneal biomechanics in neovascular glaucoma
Abstract Objective To evaluate the impact of Ahmed glaucoma valve (AGV) implantation on ocular biometric and corneal biomechanical parameters in patients with neovascular glaucoma (NVG), with the goal of understanding how these changes influence intraocular pressure (IOP) control, surgical outcomes,...
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BMC
2025-07-01
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| Online Access: | https://doi.org/10.1186/s13104-025-07313-0 |
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| author | Ali Azimi Alireza Attar Aidin Meshksar Hooman Razmi Mohammad Hassan Jalalpour Amirmohammad Fathian Adele Yarmohammadi |
| author_facet | Ali Azimi Alireza Attar Aidin Meshksar Hooman Razmi Mohammad Hassan Jalalpour Amirmohammad Fathian Adele Yarmohammadi |
| author_sort | Ali Azimi |
| collection | DOAJ |
| description | Abstract Objective To evaluate the impact of Ahmed glaucoma valve (AGV) implantation on ocular biometric and corneal biomechanical parameters in patients with neovascular glaucoma (NVG), with the goal of understanding how these changes influence intraocular pressure (IOP) control, surgical outcomes, and long-term prognosis. Results Eighteen NVG patients (mean age: 57.44 ± 10.33 years) underwent AGV implantation. A significant reduction in IOP was observed, from 36.65 ± 12.3 mmHg preoperatively to 15.5 ± 2.64 mmHg postoperatively (p < 0.001). Axial length decreased from 23.42 ± 0.76 mm to 23.21 ± 0.76 mm (p < 0.001), while anterior chamber depth increased significantly (p = 0.037). Both corneal keratometry and central corneal thickness showed significant postoperative decreases (p < 0.001). Corneal biomechanical parameters such as peak distance and deformation amplitude increased significantly (p = 0.004 and p = 0.001, respectively), whereas no significant changes were noted in applanation lengths and velocities (p > 0.05). These findings suggest that AGV implantation leads to substantial alterations in ocular structure and biomechanics, which may contribute to improved clinical outcomes in NVG management. |
| format | Article |
| id | doaj-art-d36b9c402d8b4684bafb52382fe26d3a |
| institution | Kabale University |
| issn | 1756-0500 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj-art-d36b9c402d8b4684bafb52382fe26d3a2025-08-20T04:01:25ZengBMCBMC Research Notes1756-05002025-07-011811910.1186/s13104-025-07313-0Short-term effects of Ahmed valve implantation on ocular biometry and corneal biomechanics in neovascular glaucomaAli Azimi0Alireza Attar1Aidin Meshksar2Hooman Razmi3Mohammad Hassan Jalalpour4Amirmohammad Fathian5Adele Yarmohammadi6Department of Ophthalmology, Poostchi Ophthalmology Research Center, School of Medicine, Shiraz University of Medical SciencesDepartment of Ophthalmology, Poostchi Ophthalmology Research Center, School of Medicine, Shiraz University of Medical SciencesDepartment of Ophthalmology, Poostchi Ophthalmology Research Center, School of Medicine, Shiraz University of Medical SciencesDepartment of Ophthalmology, Poostchi Ophthalmology Research Center, School of Medicine, Shiraz University of Medical SciencesDepartment of Ophthalmology, Poostchi Ophthalmology Research Center, School of Medicine, Shiraz University of Medical SciencesDepartment of Ophthalmology, Poostchi Ophthalmology Research Center, School of Medicine, Shiraz University of Medical SciencesUC San Diego Shiley Eye InstituteAbstract Objective To evaluate the impact of Ahmed glaucoma valve (AGV) implantation on ocular biometric and corneal biomechanical parameters in patients with neovascular glaucoma (NVG), with the goal of understanding how these changes influence intraocular pressure (IOP) control, surgical outcomes, and long-term prognosis. Results Eighteen NVG patients (mean age: 57.44 ± 10.33 years) underwent AGV implantation. A significant reduction in IOP was observed, from 36.65 ± 12.3 mmHg preoperatively to 15.5 ± 2.64 mmHg postoperatively (p < 0.001). Axial length decreased from 23.42 ± 0.76 mm to 23.21 ± 0.76 mm (p < 0.001), while anterior chamber depth increased significantly (p = 0.037). Both corneal keratometry and central corneal thickness showed significant postoperative decreases (p < 0.001). Corneal biomechanical parameters such as peak distance and deformation amplitude increased significantly (p = 0.004 and p = 0.001, respectively), whereas no significant changes were noted in applanation lengths and velocities (p > 0.05). These findings suggest that AGV implantation leads to substantial alterations in ocular structure and biomechanics, which may contribute to improved clinical outcomes in NVG management.https://doi.org/10.1186/s13104-025-07313-0Ahmed glaucoma valve implantationNeovascular glaucomaCorneal biomechanical |
| spellingShingle | Ali Azimi Alireza Attar Aidin Meshksar Hooman Razmi Mohammad Hassan Jalalpour Amirmohammad Fathian Adele Yarmohammadi Short-term effects of Ahmed valve implantation on ocular biometry and corneal biomechanics in neovascular glaucoma BMC Research Notes Ahmed glaucoma valve implantation Neovascular glaucoma Corneal biomechanical |
| title | Short-term effects of Ahmed valve implantation on ocular biometry and corneal biomechanics in neovascular glaucoma |
| title_full | Short-term effects of Ahmed valve implantation on ocular biometry and corneal biomechanics in neovascular glaucoma |
| title_fullStr | Short-term effects of Ahmed valve implantation on ocular biometry and corneal biomechanics in neovascular glaucoma |
| title_full_unstemmed | Short-term effects of Ahmed valve implantation on ocular biometry and corneal biomechanics in neovascular glaucoma |
| title_short | Short-term effects of Ahmed valve implantation on ocular biometry and corneal biomechanics in neovascular glaucoma |
| title_sort | short term effects of ahmed valve implantation on ocular biometry and corneal biomechanics in neovascular glaucoma |
| topic | Ahmed glaucoma valve implantation Neovascular glaucoma Corneal biomechanical |
| url | https://doi.org/10.1186/s13104-025-07313-0 |
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