Descriptive analyses and risk of death due to Ebola Virus Disease, West Africa, 2014
Introduction: Since the first case of Ebola virus disease (EVD) in Guinea in 2013, major outbreaks have been reported in West Africa. Methodology: Cases and fatalities of EVD caused by Zaire Ebola virus (ZEBOV) were evaluated, and the risks of dying in the general population and in healthcare worke...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Journal of Infection in Developing Countries
2015-12-01
|
| Series: | Journal of Infection in Developing Countries |
| Subjects: | |
| Online Access: | https://jidc.org/index.php/journal/article/view/6484 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850036719430139904 |
|---|---|
| author | Folorunso Oludayo Fasina Olubukola T. Adenubi Samuel T. Ogundare Aminu Shittu Dauda G. Bwala Modupe M. Fasina |
| author_facet | Folorunso Oludayo Fasina Olubukola T. Adenubi Samuel T. Ogundare Aminu Shittu Dauda G. Bwala Modupe M. Fasina |
| author_sort | Folorunso Oludayo Fasina |
| collection | DOAJ |
| description | Introduction: Since the first case of Ebola virus disease (EVD) in Guinea in 2013, major outbreaks have been reported in West Africa.
Methodology: Cases and fatalities of EVD caused by Zaire Ebola virus (ZEBOV) were evaluated, and the risks of dying in the general population and in healthcare workers were assessed.
Results: The case fatality rate estimated for EVD was 76.4% in 20 studies. Cumulative proportion of fatal cases in West Africa was 42.9%, 30.1%, and 64.2% in Liberia, Sierra Leone, and Guinea, respectively. The proportion of total deaths in Liberia, Sierra Leone, and Guinea was 42.5%, 35.8%, and 21.6%, respectively. Healthcare workers were at higher risk of dying compared with the general public, and the same applied to intense transmission countries and to countries with sufficient bed capacities. The declaration of a health emergency “out-of-control” situation by the World Health Organization on 8 August 2014 reduced the risk of death among patients. Factors including deplorable healthcare delivery infrastructure in war-ravaged regions of Africa, the impotence of governments to enforce public health regulations, and the loss of confidence in public healthcare delivery programs were key among others factors that enhanced the spread and magnitude of outbreaks.
Conclusions: The findings underscore the need for an overall re-appraisal of the healthcare systems in African countries and the ability to cope with widespread epidemic challenges. Outbreaks like that of Ebola diseases should be handled not just as a medical emergency but also a socio-economic problem with significant negative economic impacts. |
| format | Article |
| id | doaj-art-d3692e0974a446a38d18a4e850e86ef9 |
| institution | DOAJ |
| issn | 1972-2680 |
| language | English |
| publishDate | 2015-12-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-d3692e0974a446a38d18a4e850e86ef92025-08-20T02:57:04ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802015-12-0191210.3855/jidc.6484Descriptive analyses and risk of death due to Ebola Virus Disease, West Africa, 2014Folorunso Oludayo Fasina0Olubukola T. Adenubi1Samuel T. Ogundare2Aminu Shittu3Dauda G. Bwala4Modupe M. Fasina5University of Pretoria, Pretoria, South AfricaUniversity of Pretoria, Pretoria, South AfricaUniversity of Pretoria, Pretoria, South AfricaFaculty of Veterinary Medicine, Sokoto, NigeriaUniversity of Pretoria, Pretoria, South AfricaUniversity of Pretoria, Pretoria, South AfricaIntroduction: Since the first case of Ebola virus disease (EVD) in Guinea in 2013, major outbreaks have been reported in West Africa. Methodology: Cases and fatalities of EVD caused by Zaire Ebola virus (ZEBOV) were evaluated, and the risks of dying in the general population and in healthcare workers were assessed. Results: The case fatality rate estimated for EVD was 76.4% in 20 studies. Cumulative proportion of fatal cases in West Africa was 42.9%, 30.1%, and 64.2% in Liberia, Sierra Leone, and Guinea, respectively. The proportion of total deaths in Liberia, Sierra Leone, and Guinea was 42.5%, 35.8%, and 21.6%, respectively. Healthcare workers were at higher risk of dying compared with the general public, and the same applied to intense transmission countries and to countries with sufficient bed capacities. The declaration of a health emergency “out-of-control” situation by the World Health Organization on 8 August 2014 reduced the risk of death among patients. Factors including deplorable healthcare delivery infrastructure in war-ravaged regions of Africa, the impotence of governments to enforce public health regulations, and the loss of confidence in public healthcare delivery programs were key among others factors that enhanced the spread and magnitude of outbreaks. Conclusions: The findings underscore the need for an overall re-appraisal of the healthcare systems in African countries and the ability to cope with widespread epidemic challenges. Outbreaks like that of Ebola diseases should be handled not just as a medical emergency but also a socio-economic problem with significant negative economic impacts.https://jidc.org/index.php/journal/article/view/6484EbolaWest Africacase fatality ratefilovirus |
| spellingShingle | Folorunso Oludayo Fasina Olubukola T. Adenubi Samuel T. Ogundare Aminu Shittu Dauda G. Bwala Modupe M. Fasina Descriptive analyses and risk of death due to Ebola Virus Disease, West Africa, 2014 Journal of Infection in Developing Countries Ebola West Africa case fatality rate filovirus |
| title | Descriptive analyses and risk of death due to Ebola Virus Disease, West Africa, 2014 |
| title_full | Descriptive analyses and risk of death due to Ebola Virus Disease, West Africa, 2014 |
| title_fullStr | Descriptive analyses and risk of death due to Ebola Virus Disease, West Africa, 2014 |
| title_full_unstemmed | Descriptive analyses and risk of death due to Ebola Virus Disease, West Africa, 2014 |
| title_short | Descriptive analyses and risk of death due to Ebola Virus Disease, West Africa, 2014 |
| title_sort | descriptive analyses and risk of death due to ebola virus disease west africa 2014 |
| topic | Ebola West Africa case fatality rate filovirus |
| url | https://jidc.org/index.php/journal/article/view/6484 |
| work_keys_str_mv | AT folorunsooludayofasina descriptiveanalysesandriskofdeathduetoebolavirusdiseasewestafrica2014 AT olubukolatadenubi descriptiveanalysesandriskofdeathduetoebolavirusdiseasewestafrica2014 AT samueltogundare descriptiveanalysesandriskofdeathduetoebolavirusdiseasewestafrica2014 AT aminushittu descriptiveanalysesandriskofdeathduetoebolavirusdiseasewestafrica2014 AT daudagbwala descriptiveanalysesandriskofdeathduetoebolavirusdiseasewestafrica2014 AT modupemfasina descriptiveanalysesandriskofdeathduetoebolavirusdiseasewestafrica2014 |