Risk factors of dyspeptic syndrome in patients staying in a tuberculosis in-patient unit and the state of intestinal microflora of patients before the start of anti-tuberculosis therapy
The article describes risk factors for the development of intestinal indigestion syndrome (IIS) in 109 patients with tuberculosis while they were receiving anti-tuberculosis chemotherapy (ATCT) and the results of assessment of the intestinal microbial population in 30 patients with tuberculosis befo...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2022-05-01
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| Series: | Туберкулез и болезни лёгких |
| Subjects: | |
| Online Access: | https://www.tibl-journal.com/jour/article/view/1633 |
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| author | А. А. Kholodov Yu. V. Zakharova L. Yu. Otdushkina T. V. Pyanzova |
| author_facet | А. А. Kholodov Yu. V. Zakharova L. Yu. Otdushkina T. V. Pyanzova |
| author_sort | А. А. Kholodov |
| collection | DOAJ |
| description | The article describes risk factors for the development of intestinal indigestion syndrome (IIS) in 109 patients with tuberculosis while they were receiving anti-tuberculosis chemotherapy (ATCT) and the results of assessment of the intestinal microbial population in 30 patients with tuberculosis before chemotherapy start. The following factors made significant contribution to development of intestinal indigestion syndrome: HIV infection, the number of doses of anti-tuberculosis drugs taken, and chronic gastrointestinal diseases. Even before the start of chemotherapy, the patients had disorders of the intestinal microflora, which were characterized by a decrease in the quantity of obligate bacteria, and higher frequency and number of facultative and transient bacteria. |
| format | Article |
| id | doaj-art-d368558589874ec0a8d6ae9072755962 |
| institution | OA Journals |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2022-05-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-d368558589874ec0a8d6ae90727559622025-08-20T01:47:41ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062022-05-011004465110.21292/2075-1230-2022-100-4-46-511628Risk factors of dyspeptic syndrome in patients staying in a tuberculosis in-patient unit and the state of intestinal microflora of patients before the start of anti-tuberculosis therapyА. А. Kholodov0Yu. V. Zakharova1L. Yu. Otdushkina2T. V. Pyanzova3Kemerovo State Medical UniversityKemerovo State Medical UniversityKemerovo State Medical UniversityKemerovo State Medical UniversityThe article describes risk factors for the development of intestinal indigestion syndrome (IIS) in 109 patients with tuberculosis while they were receiving anti-tuberculosis chemotherapy (ATCT) and the results of assessment of the intestinal microbial population in 30 patients with tuberculosis before chemotherapy start. The following factors made significant contribution to development of intestinal indigestion syndrome: HIV infection, the number of doses of anti-tuberculosis drugs taken, and chronic gastrointestinal diseases. Even before the start of chemotherapy, the patients had disorders of the intestinal microflora, which were characterized by a decrease in the quantity of obligate bacteria, and higher frequency and number of facultative and transient bacteria.https://www.tibl-journal.com/jour/article/view/1633anti-tuberculosis chemotherapyintestinal microfloraintestinal indigestion syndrome |
| spellingShingle | А. А. Kholodov Yu. V. Zakharova L. Yu. Otdushkina T. V. Pyanzova Risk factors of dyspeptic syndrome in patients staying in a tuberculosis in-patient unit and the state of intestinal microflora of patients before the start of anti-tuberculosis therapy Туберкулез и болезни лёгких anti-tuberculosis chemotherapy intestinal microflora intestinal indigestion syndrome |
| title | Risk factors of dyspeptic syndrome in patients staying in a tuberculosis in-patient unit and the state of intestinal microflora of patients before the start of anti-tuberculosis therapy |
| title_full | Risk factors of dyspeptic syndrome in patients staying in a tuberculosis in-patient unit and the state of intestinal microflora of patients before the start of anti-tuberculosis therapy |
| title_fullStr | Risk factors of dyspeptic syndrome in patients staying in a tuberculosis in-patient unit and the state of intestinal microflora of patients before the start of anti-tuberculosis therapy |
| title_full_unstemmed | Risk factors of dyspeptic syndrome in patients staying in a tuberculosis in-patient unit and the state of intestinal microflora of patients before the start of anti-tuberculosis therapy |
| title_short | Risk factors of dyspeptic syndrome in patients staying in a tuberculosis in-patient unit and the state of intestinal microflora of patients before the start of anti-tuberculosis therapy |
| title_sort | risk factors of dyspeptic syndrome in patients staying in a tuberculosis in patient unit and the state of intestinal microflora of patients before the start of anti tuberculosis therapy |
| topic | anti-tuberculosis chemotherapy intestinal microflora intestinal indigestion syndrome |
| url | https://www.tibl-journal.com/jour/article/view/1633 |
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