A Case of Hairy Cell Leukemia Diagnosed Simultaneously with Lymphoplasmacytic Lymphoma by Anti-CD Antibody Microarray Method

The paper deals with a combined case of hairy cell leukemia and lymphoplasmacytic lymphoma with IgMκ paraprotein secretion. The use of anti-CD antibody microarray enabled the simultaneous assessment of immunophenotype as well as morphological and cytochemical analysis. Small populations of hairy (3...

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Bibliographic Details
Main Authors: AN Khvastunova, LS Al-Radi, OS Fedyanina, SA Lugovskaya, SA Kuznetsova
Format: Article
Language:Russian
Published: Practical Medicine Publishing House 2019-05-01
Series:Клиническая онкогематология
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Online Access: http://bloodjournal.ru/wp-content/uploads/2019/06/1.pdf
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Summary:The paper deals with a combined case of hairy cell leukemia and lymphoplasmacytic lymphoma with IgMκ paraprotein secretion. The use of anti-CD antibody microarray enabled the simultaneous assessment of immunophenotype as well as morphological and cytochemical analysis. Small populations of hairy (3 % of total lymphocyte count) and plasma (2 %) cells including Mott cells (0.2 %) were found in the peripheral blood of a patient with leukopenia. The results obtained by the anti-CD antibody microarray method speeded up provisional diagnosis which was later confirmed by standard diagnostic methods.
ISSN:1997-6933
2500-2139