Propofol-Based Sedation Does Not Increase Rate of Complication during Percutaneous Endoscopic Gastrostomy Procedure

Objectives. To evaluate and compare the complication rate of sedation with or without propofol regimen for percutaneous endoscopic gastrostomy (PEG) in a hospital in Thailand. Subjects and Methods. A total of 198 patients underwent PEG procedures by using intravenous sedation (IVS) from Siriraj Hosp...

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Main Authors: Somchai Amornyotin, Wiyada Chalayonnavin, Siriporn Kongphlay
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2011/134819
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author Somchai Amornyotin
Wiyada Chalayonnavin
Siriporn Kongphlay
author_facet Somchai Amornyotin
Wiyada Chalayonnavin
Siriporn Kongphlay
author_sort Somchai Amornyotin
collection DOAJ
description Objectives. To evaluate and compare the complication rate of sedation with or without propofol regimen for percutaneous endoscopic gastrostomy (PEG) in a hospital in Thailand. Subjects and Methods. A total of 198 patients underwent PEG procedures by using intravenous sedation (IVS) from Siriraj Hospital, Thailand from August 2006 to January 2009. The primary outcome variable was the overall complication rate. The secondary outcome variables were sedation and procedure related complications, and mortality rate. Results. After matching ASA physical status and indications of procedure, there were 92 PEG procedures in propofol based sedation group (A) and 20 PEG procedures in non-propofol based sedation group (B). All sedation was given by residents or anesthetic nurses directly supervised by staff anesthesiologist in the endoscopy room. There were no significant differences in patients' characteristics, sedation time, indication, complications, anesthetic personnel and mortality rate between the two groups. All complications were easily treated, with no adverse sequelae. Mean dose of fentanyl and midazolam in group A was significantly lower than in group B. Conclusion. Propofol-based sedation does not increase rate of complication during PEG procedure. Additionally, IVS of PEG procedure is relatively safe and effective when performed by physicians in training. Serious complications are none.
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spelling doaj-art-d35cd044c2ce4797a4ba2ccd73f5340a2025-02-03T01:32:36ZengWileyGastroenterology Research and Practice1687-61211687-630X2011-01-01201110.1155/2011/134819134819Propofol-Based Sedation Does Not Increase Rate of Complication during Percutaneous Endoscopic Gastrostomy ProcedureSomchai Amornyotin0Wiyada Chalayonnavin1Siriporn Kongphlay2Department of Anesthesiology, Siriraj GI Endoscopy Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, ThailandDepartment of Anesthesiology, Siriraj GI Endoscopy Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, ThailandDepartment of Anesthesiology, Siriraj GI Endoscopy Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, ThailandObjectives. To evaluate and compare the complication rate of sedation with or without propofol regimen for percutaneous endoscopic gastrostomy (PEG) in a hospital in Thailand. Subjects and Methods. A total of 198 patients underwent PEG procedures by using intravenous sedation (IVS) from Siriraj Hospital, Thailand from August 2006 to January 2009. The primary outcome variable was the overall complication rate. The secondary outcome variables were sedation and procedure related complications, and mortality rate. Results. After matching ASA physical status and indications of procedure, there were 92 PEG procedures in propofol based sedation group (A) and 20 PEG procedures in non-propofol based sedation group (B). All sedation was given by residents or anesthetic nurses directly supervised by staff anesthesiologist in the endoscopy room. There were no significant differences in patients' characteristics, sedation time, indication, complications, anesthetic personnel and mortality rate between the two groups. All complications were easily treated, with no adverse sequelae. Mean dose of fentanyl and midazolam in group A was significantly lower than in group B. Conclusion. Propofol-based sedation does not increase rate of complication during PEG procedure. Additionally, IVS of PEG procedure is relatively safe and effective when performed by physicians in training. Serious complications are none.http://dx.doi.org/10.1155/2011/134819
spellingShingle Somchai Amornyotin
Wiyada Chalayonnavin
Siriporn Kongphlay
Propofol-Based Sedation Does Not Increase Rate of Complication during Percutaneous Endoscopic Gastrostomy Procedure
Gastroenterology Research and Practice
title Propofol-Based Sedation Does Not Increase Rate of Complication during Percutaneous Endoscopic Gastrostomy Procedure
title_full Propofol-Based Sedation Does Not Increase Rate of Complication during Percutaneous Endoscopic Gastrostomy Procedure
title_fullStr Propofol-Based Sedation Does Not Increase Rate of Complication during Percutaneous Endoscopic Gastrostomy Procedure
title_full_unstemmed Propofol-Based Sedation Does Not Increase Rate of Complication during Percutaneous Endoscopic Gastrostomy Procedure
title_short Propofol-Based Sedation Does Not Increase Rate of Complication during Percutaneous Endoscopic Gastrostomy Procedure
title_sort propofol based sedation does not increase rate of complication during percutaneous endoscopic gastrostomy procedure
url http://dx.doi.org/10.1155/2011/134819
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AT wiyadachalayonnavin propofolbasedsedationdoesnotincreaserateofcomplicationduringpercutaneousendoscopicgastrostomyprocedure
AT siripornkongphlay propofolbasedsedationdoesnotincreaserateofcomplicationduringpercutaneousendoscopicgastrostomyprocedure