Unveiling the brain mechanism underlying depression: 12 Years of insights from bibliometric and visualization analysis

Depression is a common but serious mental health illness affected human’s physiology and psychology. In contemporary times, neurophysiological research on depression has emerged as a prominent area of investigation, yet there remains a paucity of review elucidating the central mechanisms of depressi...

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Main Authors: Donghai Wu, Siying Qu, Haiju Sun, Shuting Zhou, Xinyuan Qu, Yutian Chen, Hantong Hu, Xiaoyu Li
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Brain Research Bulletin
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Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025000589
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author Donghai Wu
Siying Qu
Haiju Sun
Shuting Zhou
Xinyuan Qu
Yutian Chen
Hantong Hu
Xiaoyu Li
author_facet Donghai Wu
Siying Qu
Haiju Sun
Shuting Zhou
Xinyuan Qu
Yutian Chen
Hantong Hu
Xiaoyu Li
author_sort Donghai Wu
collection DOAJ
description Depression is a common but serious mental health illness affected human’s physiology and psychology. In contemporary times, neurophysiological research on depression has emerged as a prominent area of investigation, yet there remains a paucity of review elucidating the central mechanisms of depression in the brain. Consequently, we undertook a bibliometric analysis and visualization assessment to underscore recent advancements in research pertaining to the neural underpinnings of depression. By employing these methods, we have collected articles spanning the period from 2013 to 2024, shedding light on the latest insights into the brain mechanisms associated with depression. Bibliometric analysis found 16327 research papers in the field of brain mechanism underlying depression, overall showing a sustained growth trend. Through meticulous analysis of collected data on institutions and countries, authors, co-cited literature, keywords, etc., this paper humbly aims to tentatively identify future research hotspots and frontiers, hoping to modestly contribute to and stimulate further scholarly progress in the field.
format Article
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institution DOAJ
issn 1873-2747
language English
publishDate 2025-03-01
publisher Elsevier
record_format Article
series Brain Research Bulletin
spelling doaj-art-d3515eded95041dab26c2a30d312525d2025-08-20T02:47:21ZengElsevierBrain Research Bulletin1873-27472025-03-0122211124610.1016/j.brainresbull.2025.111246Unveiling the brain mechanism underlying depression: 12 Years of insights from bibliometric and visualization analysisDonghai Wu0Siying Qu1Haiju Sun2Shuting Zhou3Xinyuan Qu4Yutian Chen5Hantong Hu6Xiaoyu Li7The Third Affiliated Hospital of Zhejiang Chinese Medical University (Zhongshan Hospital of Zhejiang Province), Hangzhou, Zhejiang 310053, China; Key Laboratory of Acupuncture and Neurology of Zhejiang Province, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, ChinaThe Third Affiliated Hospital of Zhejiang Chinese Medical University (Zhongshan Hospital of Zhejiang Province), Hangzhou, Zhejiang 310053, ChinaThe First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang 310053, ChinaThe Third Affiliated Hospital of Zhejiang Chinese Medical University (Zhongshan Hospital of Zhejiang Province), Hangzhou, Zhejiang 310053, China; Key Laboratory of Acupuncture and Neurology of Zhejiang Province, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, ChinaThe Third Affiliated Hospital of Zhejiang Chinese Medical University (Zhongshan Hospital of Zhejiang Province), Hangzhou, Zhejiang 310053, ChinaThe Third Affiliated Hospital of Zhejiang Chinese Medical University (Zhongshan Hospital of Zhejiang Province), Hangzhou, Zhejiang 310053, ChinaThe Third Affiliated Hospital of Zhejiang Chinese Medical University (Zhongshan Hospital of Zhejiang Province), Hangzhou, Zhejiang 310053, ChinaThe Third Affiliated Hospital of Zhejiang Chinese Medical University (Zhongshan Hospital of Zhejiang Province), Hangzhou, Zhejiang 310053, China; Key Laboratory of Acupuncture and Neurology of Zhejiang Province, The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China; Correspondence to: Key Laboratory of Acupuncture and Neurology of Zhejiang Province, The Third Clinical Medical College, Zhejiang Chinese Medical University, 548 Binwen Road, Binjiang District, Hangzhou, Zhejiang 310053, China.Depression is a common but serious mental health illness affected human’s physiology and psychology. In contemporary times, neurophysiological research on depression has emerged as a prominent area of investigation, yet there remains a paucity of review elucidating the central mechanisms of depression in the brain. Consequently, we undertook a bibliometric analysis and visualization assessment to underscore recent advancements in research pertaining to the neural underpinnings of depression. By employing these methods, we have collected articles spanning the period from 2013 to 2024, shedding light on the latest insights into the brain mechanisms associated with depression. Bibliometric analysis found 16327 research papers in the field of brain mechanism underlying depression, overall showing a sustained growth trend. Through meticulous analysis of collected data on institutions and countries, authors, co-cited literature, keywords, etc., this paper humbly aims to tentatively identify future research hotspots and frontiers, hoping to modestly contribute to and stimulate further scholarly progress in the field.http://www.sciencedirect.com/science/article/pii/S0361923025000589DepressionBrain mechanismVOSviewerCitespaceBibliometric analysis
spellingShingle Donghai Wu
Siying Qu
Haiju Sun
Shuting Zhou
Xinyuan Qu
Yutian Chen
Hantong Hu
Xiaoyu Li
Unveiling the brain mechanism underlying depression: 12 Years of insights from bibliometric and visualization analysis
Brain Research Bulletin
Depression
Brain mechanism
VOSviewer
Citespace
Bibliometric analysis
title Unveiling the brain mechanism underlying depression: 12 Years of insights from bibliometric and visualization analysis
title_full Unveiling the brain mechanism underlying depression: 12 Years of insights from bibliometric and visualization analysis
title_fullStr Unveiling the brain mechanism underlying depression: 12 Years of insights from bibliometric and visualization analysis
title_full_unstemmed Unveiling the brain mechanism underlying depression: 12 Years of insights from bibliometric and visualization analysis
title_short Unveiling the brain mechanism underlying depression: 12 Years of insights from bibliometric and visualization analysis
title_sort unveiling the brain mechanism underlying depression 12 years of insights from bibliometric and visualization analysis
topic Depression
Brain mechanism
VOSviewer
Citespace
Bibliometric analysis
url http://www.sciencedirect.com/science/article/pii/S0361923025000589
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