Metabolic reprogramming in lung cancer and its clinical implication
Lung cancer has posed a significant challenge to global health, and related study has been a hot topic in oncology. This article focuses on metabolic reprogramming of lung cancer cells, a process to adapt to energy demands and biosynthetic needs, supporting the proliferation and development of tumor...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-12-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2024.1516650/full |
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| author | Qingqiu Huang Lisha Fan Mingjing Gong Juntong Ren Chen Chen Shenglong Xie |
| author_facet | Qingqiu Huang Lisha Fan Mingjing Gong Juntong Ren Chen Chen Shenglong Xie |
| author_sort | Qingqiu Huang |
| collection | DOAJ |
| description | Lung cancer has posed a significant challenge to global health, and related study has been a hot topic in oncology. This article focuses on metabolic reprogramming of lung cancer cells, a process to adapt to energy demands and biosynthetic needs, supporting the proliferation and development of tumor cells. In this study, the latest studies on lung cancer tumor metabolism were reviewed, including the impact of metabolic products and metabolic enzymes on the occurrence and development of lung cancer, as well as the progress in the field of lung cancer treatment targeting relevant metabolic pathways. This provides some promising potential directions into exploring lung cancer tumor metabolism and helps researchers to better understand lung cancer. |
| format | Article |
| id | doaj-art-d34b9915e95d41a48668b7896306c1bc |
| institution | OA Journals |
| issn | 1663-9812 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj-art-d34b9915e95d41a48668b7896306c1bc2025-08-20T01:57:55ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122024-12-011510.3389/fphar.2024.15166501516650Metabolic reprogramming in lung cancer and its clinical implicationQingqiu Huang0Lisha Fan1Mingjing Gong2Juntong Ren3Chen Chen4Shenglong Xie5Department of Thoracic Surgery, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Pulmonary and Critical Care Medicine, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaSichuan Province Revolutionary Disable Armyman Rehab, The First Veterans Hospital Of Sichuan Province, Chengdu, ChinaSchool of Pharmaceutical Sciences, Guizhou University, Guiyang, ChinaDepartment of Outpatient, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Thoracic Surgery, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaLung cancer has posed a significant challenge to global health, and related study has been a hot topic in oncology. This article focuses on metabolic reprogramming of lung cancer cells, a process to adapt to energy demands and biosynthetic needs, supporting the proliferation and development of tumor cells. In this study, the latest studies on lung cancer tumor metabolism were reviewed, including the impact of metabolic products and metabolic enzymes on the occurrence and development of lung cancer, as well as the progress in the field of lung cancer treatment targeting relevant metabolic pathways. This provides some promising potential directions into exploring lung cancer tumor metabolism and helps researchers to better understand lung cancer.https://www.frontiersin.org/articles/10.3389/fphar.2024.1516650/fullmetabolic reprogramminglung cancerglucoselipid metabolismamino acid metabolism |
| spellingShingle | Qingqiu Huang Lisha Fan Mingjing Gong Juntong Ren Chen Chen Shenglong Xie Metabolic reprogramming in lung cancer and its clinical implication Frontiers in Pharmacology metabolic reprogramming lung cancer glucose lipid metabolism amino acid metabolism |
| title | Metabolic reprogramming in lung cancer and its clinical implication |
| title_full | Metabolic reprogramming in lung cancer and its clinical implication |
| title_fullStr | Metabolic reprogramming in lung cancer and its clinical implication |
| title_full_unstemmed | Metabolic reprogramming in lung cancer and its clinical implication |
| title_short | Metabolic reprogramming in lung cancer and its clinical implication |
| title_sort | metabolic reprogramming in lung cancer and its clinical implication |
| topic | metabolic reprogramming lung cancer glucose lipid metabolism amino acid metabolism |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2024.1516650/full |
| work_keys_str_mv | AT qingqiuhuang metabolicreprogramminginlungcanceranditsclinicalimplication AT lishafan metabolicreprogramminginlungcanceranditsclinicalimplication AT mingjinggong metabolicreprogramminginlungcanceranditsclinicalimplication AT juntongren metabolicreprogramminginlungcanceranditsclinicalimplication AT chenchen metabolicreprogramminginlungcanceranditsclinicalimplication AT shenglongxie metabolicreprogramminginlungcanceranditsclinicalimplication |