Low dose baclofen and standard dose acamprosate had comparable changes in brain glutamate, brain Gamma amino butyric acid (GABA) and craving among patients with alcohol dependence syndrome: A 1H-MRS based open label randomized study

Low dose baclofen and standard dose acamprosate had comparable changes in brain glutamate, brain Gamma amino butyric acid (GABA) and craving among patients with alcohol dependence syndrome: A 1H-MRS based open label randomized study

Background: Understanding of the mechanism of action of Baclofen as anticraving inalcohol dependence syndrome (ADS) is limited. Aim: Our study aimed to examine and compareearly changes in brain glutamate and GABA with Baclofen and Acamprosate among patients with alcohol dependence syndrome. Material...

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Bibliographic Details
Main Authors: Akhil Kesan, Pranjal Dey, Sourav Khanra, Samiksha Singhai, Monalisa Boro
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Industrial Psychiatry Journal
Subjects:
1h-mrs
acamprosate
alcohol
anticraving
baclofen
gaba
glutamate
Online Access:https://journals.lww.com/10.4103/ipj.ipj_187_23
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