Evaluation of the long-term memory T cell in mice after immunization with a live tularemia vaccine

Evaluation of the long-term memory T cell in mice after immunization with a live tularemia vaccine

The vaccine strain F. tularensis 15 NIIEG induces long-lived cell-mediated immunity but exhibits a certain reactogenicity and genetic instability. Progress in development of a vaccine against tularemia has been limited by a lack of information regarding the mechanisms required to protect against thi...

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Bibliographic Details
Main Authors: A. S. Kartseva, M. V. Silkina, G. M. Titareva, T. I. Kombarova, R. I. Mironova, V. V. Firstova
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2023-06-01
Series:Медицинская иммунология
Subjects:
fransicella tularensis
vaccine strain
memory t-cells
cd69
ifn-γ
tnf-α
cellular immunity
Online Access:https://www.mimmun.ru/mimmun/article/view/2746
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