Chronic Maternal Overnutrition and Nutritional Challenge in Adult Life Disrupt Metabolic Diurnal Rhythmicity and Clock Gene Expression in Central and Peripheral Circadian Oscillators

Chronic Maternal Overnutrition and Nutritional Challenge in Adult Life Disrupt Metabolic Diurnal Rhythmicity and Clock Gene Expression in Central and Peripheral Circadian Oscillators

In mammals, the core molecular clock genes and the overall circadian system are established during early development; during this critical period of development, maternal metabolic condition plays a major role in programming temporal metabolic regulation. Therefore, this study aimed to evaluate the...

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Bibliographic Details
Main Authors: Lucía Carolina Cano, Erika Navarrete, Juan Pablo Ochoa-Romo, Georgina Díaz, Verónica Díaz-Hernández, Rodrigo Montúfar-Chaveznava, Ivette Caldelas
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biology
Subjects:
maternal overnutrition
circadian rhythms
multigenerational inheritance
nutritional challenge
metabolic dysregulation
clock genes
Online Access:https://www.mdpi.com/2079-7737/14/5/541
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