Comparative analysis of neutrophil dynamics and disease in SARS-CoV-2 Delta and Omicron variants utilizing an in vivo feline model for COVID-19

Comparative analysis of neutrophil dynamics and disease in SARS-CoV-2 Delta and Omicron variants utilizing an in vivo feline model for COVID-19

IntroductionThe emergence of SARS-CoV-2 variants, particularly Delta (B.1.617.2) and Omicron (XBB.1.5) variants, has substantially influenced the clinical and immunological landscape of COVID-19. This study investigates the differential pathogenicity and immune responses in a feline model infected w...

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Bibliographic Details
Main Authors: Sachithra Gunasekara, Shoroq Shatnawi, Sunil More, Breya Ludwig, Sai Narayanan, Miruthula Tamil Selvan, Craig A. Miller, Jennifer M. Rudd
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
COVID-19
Delta
Omicron
immunopathogenesis
neutrophils
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1547918/full
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