Efficacy of CLT4A variants as immunoregulatory molecules among Vitiligo patients in Saudi Arabia

Efficacy of CLT4A variants as immunoregulatory molecules among Vitiligo patients in Saudi Arabia

Abstract Vitiligo is a skin depigmentation condition caused by the immune-mediated perdition of melanocytes. In vitiligo, cytotoxic T-lymphocytes damage melanocytes, causing skin depigmentation. The Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) gene has been reported to be related to vitiligo and other...

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Bibliographic Details
Main Authors: Amal F. Alshammary, Ghada BinSaif, Imran Ali Khan
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Vitiligo
rs231775
rs3087243
SNPs
CTLA4 gene
Saudi population
Online Access:https://doi.org/10.1038/s41598-025-88749-z
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