Isolated cardiac sarcoidosis: A clinical challenge

Sarcoidosis is an inflammatory disease characterised by non-caseating granulomas of unclear aetiology. Isolated cardiac sarcoidosis (ICS) is rare and occurs when there is granulomatous infiltration of myocardial tissue without evidence of extracardiac sarcoidosis. The heterogeneity in clinical manif...

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Bibliographic Details
Main Authors: Paul Njoku, Sumbal Rani, Orestis Paschalis, Emanuela Alati, Amit K.J. Mandal, Constantinos G. Missouris
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Clinical Medicine
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Online Access:http://www.sciencedirect.com/science/article/pii/S1470211824054307
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Summary:Sarcoidosis is an inflammatory disease characterised by non-caseating granulomas of unclear aetiology. Isolated cardiac sarcoidosis (ICS) is rare and occurs when there is granulomatous infiltration of myocardial tissue without evidence of extracardiac sarcoidosis. The heterogeneity in clinical manifestations often presents a diagnostic challenge which leads to delays in treatment initiation. Our case highlights the often quiescent presentation of ICS, the importance of early treatment and the diagnostic challenges that contribute to its underdiagnosis.
ISSN:1470-2118