Preparation of Magnetic Molecularly Imprinted Polymers for Selective Recognition and Determination of Clenbuterol in Pork Samples
Magnetic molecularly imprinted polymer (MMIP) was successfully synthesized with acrylamide as a functional monomer and clenbuterol (CLB) as a template molecule. The synthesized MMIPs were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier transform infrared spe...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2020/8820262 |
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| author | Yingjuan Zhao Zufei Feng Sijin Li Yan Lu Yangfan Hu Hua Fan Xinyue Zhai |
| author_facet | Yingjuan Zhao Zufei Feng Sijin Li Yan Lu Yangfan Hu Hua Fan Xinyue Zhai |
| author_sort | Yingjuan Zhao |
| collection | DOAJ |
| description | Magnetic molecularly imprinted polymer (MMIP) was successfully synthesized with acrylamide as a functional monomer and clenbuterol (CLB) as a template molecule. The synthesized MMIPs were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier transform infrared spectrometry (FT-IR). MMIPs were used to identify and bind CLB as a solid phase extraction material. The experiment data were fitted by the Freundlich isotherm adsorption model. The results show that MMIPs have excellent recognition performance for CLB. MMIPs were successfully applied as adsorbents to preconcentrated CLB in pork samples and detected by HPLC with UV. The limit of detection (LOD) and limit of quantification (LOQ) were 4.27 μg/L and 14.2 μg/L, respectively. The spiked recovery rates ranged from 94.44% to 102.29%. Therefore, the prepared MMIPs can be used for selective preconcentration of CLB content in complex animal-derived food samples. |
| format | Article |
| id | doaj-art-d30ba970a1f04c6d82b831143674ea2e |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-d30ba970a1f04c6d82b831143674ea2e2025-08-20T03:24:07ZengWileyJournal of Chemistry2090-90632090-90712020-01-01202010.1155/2020/88202628820262Preparation of Magnetic Molecularly Imprinted Polymers for Selective Recognition and Determination of Clenbuterol in Pork SamplesYingjuan Zhao0Zufei Feng1Sijin Li2Yan Lu3Yangfan Hu4Hua Fan5Xinyue Zhai6Department of Applied Chemistry, Xi’an University of Technology, Xi’an 710048, ChinaDepartment of Applied Chemistry, Xi’an University of Technology, Xi’an 710048, ChinaDepartment of Applied Chemistry, Xi’an University of Technology, Xi’an 710048, ChinaDepartment of Applied Chemistry, Xi’an University of Technology, Xi’an 710048, ChinaDepartment of Applied Chemistry, Xi’an University of Technology, Xi’an 710048, ChinaDepartment of Applied Chemistry, Xi’an University of Technology, Xi’an 710048, ChinaDepartment of Applied Chemistry, Xi’an University of Technology, Xi’an 710048, ChinaMagnetic molecularly imprinted polymer (MMIP) was successfully synthesized with acrylamide as a functional monomer and clenbuterol (CLB) as a template molecule. The synthesized MMIPs were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier transform infrared spectrometry (FT-IR). MMIPs were used to identify and bind CLB as a solid phase extraction material. The experiment data were fitted by the Freundlich isotherm adsorption model. The results show that MMIPs have excellent recognition performance for CLB. MMIPs were successfully applied as adsorbents to preconcentrated CLB in pork samples and detected by HPLC with UV. The limit of detection (LOD) and limit of quantification (LOQ) were 4.27 μg/L and 14.2 μg/L, respectively. The spiked recovery rates ranged from 94.44% to 102.29%. Therefore, the prepared MMIPs can be used for selective preconcentration of CLB content in complex animal-derived food samples.http://dx.doi.org/10.1155/2020/8820262 |
| spellingShingle | Yingjuan Zhao Zufei Feng Sijin Li Yan Lu Yangfan Hu Hua Fan Xinyue Zhai Preparation of Magnetic Molecularly Imprinted Polymers for Selective Recognition and Determination of Clenbuterol in Pork Samples Journal of Chemistry |
| title | Preparation of Magnetic Molecularly Imprinted Polymers for Selective Recognition and Determination of Clenbuterol in Pork Samples |
| title_full | Preparation of Magnetic Molecularly Imprinted Polymers for Selective Recognition and Determination of Clenbuterol in Pork Samples |
| title_fullStr | Preparation of Magnetic Molecularly Imprinted Polymers for Selective Recognition and Determination of Clenbuterol in Pork Samples |
| title_full_unstemmed | Preparation of Magnetic Molecularly Imprinted Polymers for Selective Recognition and Determination of Clenbuterol in Pork Samples |
| title_short | Preparation of Magnetic Molecularly Imprinted Polymers for Selective Recognition and Determination of Clenbuterol in Pork Samples |
| title_sort | preparation of magnetic molecularly imprinted polymers for selective recognition and determination of clenbuterol in pork samples |
| url | http://dx.doi.org/10.1155/2020/8820262 |
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