Rubin H. Flocks and Colloidal Gold Treatments for Prostate Cancer

In the early 1950s, Rubin H. Flocks of the University of Iowa began to treat prostate cancer patients with colloidal gold (Au198) therapy, evolving his technique over nearly 25 years in 1515 patients. We reviewed the long-term outcomes of Flocks' prostate cancer patients as compared to those pa...

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Main Authors: Henry M. Rosevear, Andrew J. Lightfoot, Michael A. O'Donnell, Charles E. Platz, Stefan A. Loening, Charles E. Hawtrey
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2011.145
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author Henry M. Rosevear
Andrew J. Lightfoot
Michael A. O'Donnell
Charles E. Platz
Stefan A. Loening
Charles E. Hawtrey
author_facet Henry M. Rosevear
Andrew J. Lightfoot
Michael A. O'Donnell
Charles E. Platz
Stefan A. Loening
Charles E. Hawtrey
author_sort Henry M. Rosevear
collection DOAJ
description In the early 1950s, Rubin H. Flocks of the University of Iowa began to treat prostate cancer patients with colloidal gold (Au198) therapy, evolving his technique over nearly 25 years in 1515 patients. We reviewed the long-term outcomes of Flocks' prostate cancer patients as compared to those patients treated by other methods at the University of Iowa before Flocks' chairmanship. We reviewed archived patient records, Flocks' published data, and long-term survival data from the Iowa Tumor Registry to determine short- and long-term outcomes of Flocks' work with colloidal gold. We also reviewed the literature of Flocks' time to compare his outcomes against those of his contemporaries. The use of colloidal gold, either as primary or adjunctive therapy, provided short- and long-term survival benefit for the majority of Flocks' patients as compared to historical treatment options (p < 0.001). Flocks' use of colloidal gold for the treatment of locally advanced prostate cancer offered short- and long-term survival benefits compared to other contemporary treatments.
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spelling doaj-art-d2ee6003c9294befaf40a8d19fce62972025-02-03T01:22:24ZengWileyThe Scientific World Journal1537-744X2011-01-01111560156710.1100/tsw.2011.145Rubin H. Flocks and Colloidal Gold Treatments for Prostate CancerHenry M. Rosevear0Andrew J. Lightfoot1Michael A. O'Donnell2Charles E. Platz3Stefan A. Loening4Charles E. Hawtrey5Department of Urology, University of Iowa, Iowa City, USADepartment of Urology, University of Iowa, Iowa City, USADepartment of Urology, University of Iowa, Iowa City, USAIowa Cancer Registry, Iowa City, USAHumboldt University, Charité Hospital, Berlin, GermanyDepartment of Urology, University of Iowa, Iowa City, USAIn the early 1950s, Rubin H. Flocks of the University of Iowa began to treat prostate cancer patients with colloidal gold (Au198) therapy, evolving his technique over nearly 25 years in 1515 patients. We reviewed the long-term outcomes of Flocks' prostate cancer patients as compared to those patients treated by other methods at the University of Iowa before Flocks' chairmanship. We reviewed archived patient records, Flocks' published data, and long-term survival data from the Iowa Tumor Registry to determine short- and long-term outcomes of Flocks' work with colloidal gold. We also reviewed the literature of Flocks' time to compare his outcomes against those of his contemporaries. The use of colloidal gold, either as primary or adjunctive therapy, provided short- and long-term survival benefit for the majority of Flocks' patients as compared to historical treatment options (p < 0.001). Flocks' use of colloidal gold for the treatment of locally advanced prostate cancer offered short- and long-term survival benefits compared to other contemporary treatments.http://dx.doi.org/10.1100/tsw.2011.145
spellingShingle Henry M. Rosevear
Andrew J. Lightfoot
Michael A. O'Donnell
Charles E. Platz
Stefan A. Loening
Charles E. Hawtrey
Rubin H. Flocks and Colloidal Gold Treatments for Prostate Cancer
The Scientific World Journal
title Rubin H. Flocks and Colloidal Gold Treatments for Prostate Cancer
title_full Rubin H. Flocks and Colloidal Gold Treatments for Prostate Cancer
title_fullStr Rubin H. Flocks and Colloidal Gold Treatments for Prostate Cancer
title_full_unstemmed Rubin H. Flocks and Colloidal Gold Treatments for Prostate Cancer
title_short Rubin H. Flocks and Colloidal Gold Treatments for Prostate Cancer
title_sort rubin h flocks and colloidal gold treatments for prostate cancer
url http://dx.doi.org/10.1100/tsw.2011.145
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