Assessing the safety of gene therapy vectors expressing an enhanced gamma-globin gene for the cure of sickle cell anemia

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Main Author: Stefano Rivella
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050125000762
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author Stefano Rivella
author_facet Stefano Rivella
author_sort Stefano Rivella
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publishDate 2025-06-01
publisher Elsevier
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series Molecular Therapy: Methods & Clinical Development
spelling doaj-art-d2ecd1454d454b37980fe73c1bb4ff8a2025-08-20T02:56:09ZengElsevierMolecular Therapy: Methods & Clinical Development2329-05012025-06-0133210148110.1016/j.omtm.2025.101481Assessing the safety of gene therapy vectors expressing an enhanced gamma-globin gene for the cure of sickle cell anemiaStefano Rivella0Department of Pediatrics, Hematology, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA; University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA; Raymond G. Perelman Center for Cellular and Molecular Therapeutics-The Children’s Hospital of Philadelphia, Philadelphia, PA, USA; Penn Center for Musculoskeletal Disorders, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA; Penn Institute for RNA Innovation, University of Pennsylvania, Philadelphia, PA, USA; Corresponding author: Stefano Rivella, Ph.D., Children’s Hospital of Philadelphia, Abramson Research Center, 3615 Civic Center Blvd, Room 316B, Philadelphia, PA 19104, USA.http://www.sciencedirect.com/science/article/pii/S2329050125000762
spellingShingle Stefano Rivella
Assessing the safety of gene therapy vectors expressing an enhanced gamma-globin gene for the cure of sickle cell anemia
Molecular Therapy: Methods & Clinical Development
title Assessing the safety of gene therapy vectors expressing an enhanced gamma-globin gene for the cure of sickle cell anemia
title_full Assessing the safety of gene therapy vectors expressing an enhanced gamma-globin gene for the cure of sickle cell anemia
title_fullStr Assessing the safety of gene therapy vectors expressing an enhanced gamma-globin gene for the cure of sickle cell anemia
title_full_unstemmed Assessing the safety of gene therapy vectors expressing an enhanced gamma-globin gene for the cure of sickle cell anemia
title_short Assessing the safety of gene therapy vectors expressing an enhanced gamma-globin gene for the cure of sickle cell anemia
title_sort assessing the safety of gene therapy vectors expressing an enhanced gamma globin gene for the cure of sickle cell anemia
url http://www.sciencedirect.com/science/article/pii/S2329050125000762
work_keys_str_mv AT stefanorivella assessingthesafetyofgenetherapyvectorsexpressinganenhancedgammaglobingeneforthecureofsicklecellanemia