The Impact of Transurethral Enucleation Therapeutic Approach in All-Size Benign Prostatic Obstruction Pathology: From Contemporary Technological Advances to Evidence-Based Clinical Progresses
Transurethral enucleation (TUE) has revolutionized the management of benign prostatic obstruction (BPO), offering a minimally invasive solution with superior efficacy across all prostate sizes. This review explores the advancements in TUE techniques, including Holmium Laser Enucleation of the Prosta...
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MDPI AG
2025-02-01
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| Online Access: | https://www.mdpi.com/2075-4418/15/4/416 |
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| author | Catalin-Andrei Bulai Razvan-Dragos Multescu Petrisor-Aurelian Geavlete Ana Maria Andreea Punga Adrian Militaru Bogdan-Gabriel Buzescu Cosmin-Victor Ene Cristian Mares Bogdan-Florin Geavlete |
| author_facet | Catalin-Andrei Bulai Razvan-Dragos Multescu Petrisor-Aurelian Geavlete Ana Maria Andreea Punga Adrian Militaru Bogdan-Gabriel Buzescu Cosmin-Victor Ene Cristian Mares Bogdan-Florin Geavlete |
| author_sort | Catalin-Andrei Bulai |
| collection | DOAJ |
| description | Transurethral enucleation (TUE) has revolutionized the management of benign prostatic obstruction (BPO), offering a minimally invasive solution with superior efficacy across all prostate sizes. This review explores the advancements in TUE techniques, including Holmium Laser Enucleation of the Prostate (HoLEP), Thulium Laser Enucleation of the Prostate (ThuLEP), and bipolar enucleation, highlighting their clinical benefits, safety profiles, and long-term outcomes. Compared to traditional approaches such as transurethral resection of the prostate (TURP) and open prostatectomy, TUE has been associated with reduced complication rates, shorter recovery times, and durable symptom relief. The manuscript also examines patient-centered considerations, such as quality of life improvements and preservation of sexual function, which contribute to high patient satisfaction. Furthermore, the economic advantages of TUE, driven by reduced retreatment rates and healthcare costs, underscore its value for both patients and healthcare systems. Emerging innovations, including artificial intelligence (AI), promise to further enhance procedural planning, surgical precision, and training pathways. Efforts to expand global access through cost-effective adaptations like bipolar enucleation and targeted training initiatives are paving the way for wider adoption of TUE. With its adaptability, technological advancements, and focus on patient outcomes, TUE is poised to become the global standard of care in BPO management. |
| format | Article |
| id | doaj-art-d2e4d4d1db48472d8ec72aa61fd66dd3 |
| institution | DOAJ |
| issn | 2075-4418 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj-art-d2e4d4d1db48472d8ec72aa61fd66dd32025-08-20T02:44:35ZengMDPI AGDiagnostics2075-44182025-02-0115441610.3390/diagnostics15040416The Impact of Transurethral Enucleation Therapeutic Approach in All-Size Benign Prostatic Obstruction Pathology: From Contemporary Technological Advances to Evidence-Based Clinical ProgressesCatalin-Andrei Bulai0Razvan-Dragos Multescu1Petrisor-Aurelian Geavlete2Ana Maria Andreea Punga3Adrian Militaru4Bogdan-Gabriel Buzescu5Cosmin-Victor Ene6Cristian Mares7Bogdan-Florin Geavlete8Department of Urology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Urology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Urology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Urology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Urology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Urology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Urology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Urology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Urology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaTransurethral enucleation (TUE) has revolutionized the management of benign prostatic obstruction (BPO), offering a minimally invasive solution with superior efficacy across all prostate sizes. This review explores the advancements in TUE techniques, including Holmium Laser Enucleation of the Prostate (HoLEP), Thulium Laser Enucleation of the Prostate (ThuLEP), and bipolar enucleation, highlighting their clinical benefits, safety profiles, and long-term outcomes. Compared to traditional approaches such as transurethral resection of the prostate (TURP) and open prostatectomy, TUE has been associated with reduced complication rates, shorter recovery times, and durable symptom relief. The manuscript also examines patient-centered considerations, such as quality of life improvements and preservation of sexual function, which contribute to high patient satisfaction. Furthermore, the economic advantages of TUE, driven by reduced retreatment rates and healthcare costs, underscore its value for both patients and healthcare systems. Emerging innovations, including artificial intelligence (AI), promise to further enhance procedural planning, surgical precision, and training pathways. Efforts to expand global access through cost-effective adaptations like bipolar enucleation and targeted training initiatives are paving the way for wider adoption of TUE. With its adaptability, technological advancements, and focus on patient outcomes, TUE is poised to become the global standard of care in BPO management.https://www.mdpi.com/2075-4418/15/4/416transurethral enucleationbenign prostatic obstructionlaser enucleationminimally invasive urologybipolar enucleation |
| spellingShingle | Catalin-Andrei Bulai Razvan-Dragos Multescu Petrisor-Aurelian Geavlete Ana Maria Andreea Punga Adrian Militaru Bogdan-Gabriel Buzescu Cosmin-Victor Ene Cristian Mares Bogdan-Florin Geavlete The Impact of Transurethral Enucleation Therapeutic Approach in All-Size Benign Prostatic Obstruction Pathology: From Contemporary Technological Advances to Evidence-Based Clinical Progresses Diagnostics transurethral enucleation benign prostatic obstruction laser enucleation minimally invasive urology bipolar enucleation |
| title | The Impact of Transurethral Enucleation Therapeutic Approach in All-Size Benign Prostatic Obstruction Pathology: From Contemporary Technological Advances to Evidence-Based Clinical Progresses |
| title_full | The Impact of Transurethral Enucleation Therapeutic Approach in All-Size Benign Prostatic Obstruction Pathology: From Contemporary Technological Advances to Evidence-Based Clinical Progresses |
| title_fullStr | The Impact of Transurethral Enucleation Therapeutic Approach in All-Size Benign Prostatic Obstruction Pathology: From Contemporary Technological Advances to Evidence-Based Clinical Progresses |
| title_full_unstemmed | The Impact of Transurethral Enucleation Therapeutic Approach in All-Size Benign Prostatic Obstruction Pathology: From Contemporary Technological Advances to Evidence-Based Clinical Progresses |
| title_short | The Impact of Transurethral Enucleation Therapeutic Approach in All-Size Benign Prostatic Obstruction Pathology: From Contemporary Technological Advances to Evidence-Based Clinical Progresses |
| title_sort | impact of transurethral enucleation therapeutic approach in all size benign prostatic obstruction pathology from contemporary technological advances to evidence based clinical progresses |
| topic | transurethral enucleation benign prostatic obstruction laser enucleation minimally invasive urology bipolar enucleation |
| url | https://www.mdpi.com/2075-4418/15/4/416 |
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