The Impact of Yes-Associated Protein 1 (YAP1) Expression Patterns in Locally Advanced Breast Cancer: Associations with Pathological Response and Tumor Features

The Impact of Yes-Associated Protein 1 (YAP1) Expression Patterns in Locally Advanced Breast Cancer: Associations with Pathological Response and Tumor Features

<i>Background and Objectives</i>: The Hippo pathway, via Yes-associated protein 1 (YAP1), regulates cell proliferation, apoptosis, and tissue regeneration. Aberrant YAP1 activation is linked to tumor progression and immune evasion in various cancers, including breast carcinoma, despite c...

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Bibliographic Details
Main Authors: Osman Erinc, Sabin Goktas Aydin, Taskin Erkinuresin, Ozgur Yilmaz, Ahmet Aydin, Sevinc Dagistanli, Murat Akarsu
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Medicina
Subjects:
YAP1
locally advanced breast cancer
neoadjuvant chemotherapy
axillary pCR
HER-2
Online Access:https://www.mdpi.com/1648-9144/61/7/1297
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