Pachymaran alleviates fat accumulation, hepatocyte degeneration, and injury in mice with nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive hepatic fat accumulation and is closely associated with obesity, diabetes, and hyperlipidemia.

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Main Authors: Yu Hong, Wan Min, Li Hong, Liu Xing
Format: Article
Language:English
Published: De Gruyter 2025-07-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2025-1241
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author Yu Hong
Wan Min
Li Hong
Liu Xing
author_facet Yu Hong
Wan Min
Li Hong
Liu Xing
author_sort Yu Hong
collection DOAJ
description Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive hepatic fat accumulation and is closely associated with obesity, diabetes, and hyperlipidemia.
format Article
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institution Kabale University
issn 2391-5463
language English
publishDate 2025-07-01
publisher De Gruyter
record_format Article
series Open Medicine
spelling doaj-art-d2d3bfbc1db045f2b5ae528305bdaee42025-08-20T03:56:49ZengDe GruyterOpen Medicine2391-54632025-07-0120185610.1515/med-2025-1241Pachymaran alleviates fat accumulation, hepatocyte degeneration, and injury in mice with nonalcoholic fatty liver diseaseYu Hong0Wan Min1Li Hong2Liu Xing3Medical Laboratory, Wuhan Hospital of Traditional Chinese Medicine, Wuhan, Hubei, 430050, ChinaMedical Laboratory, Wuhan Hospital of Traditional Chinese Medicine, Wuhan, Hubei, 430050, ChinaMedical Laboratory, Wuhan Hospital of Traditional Chinese Medicine, Wuhan, Hubei, 430050, ChinaMedical Laboratory, Wuhan Hospital of Traditional Chinese Medicine, No. 303, Sixin Avenue, Hanyang District, Wuhan, Hubei, 430050, ChinaNonalcoholic fatty liver disease (NAFLD) is characterized by excessive hepatic fat accumulation and is closely associated with obesity, diabetes, and hyperlipidemia.https://doi.org/10.1515/med-2025-1241pachymarannonalcoholic fatty liver diseaseadenylate-activated protein kinaseliverfat
spellingShingle Yu Hong
Wan Min
Li Hong
Liu Xing
Pachymaran alleviates fat accumulation, hepatocyte degeneration, and injury in mice with nonalcoholic fatty liver disease
Open Medicine
pachymaran
nonalcoholic fatty liver disease
adenylate-activated protein kinase
liver
fat
title Pachymaran alleviates fat accumulation, hepatocyte degeneration, and injury in mice with nonalcoholic fatty liver disease
title_full Pachymaran alleviates fat accumulation, hepatocyte degeneration, and injury in mice with nonalcoholic fatty liver disease
title_fullStr Pachymaran alleviates fat accumulation, hepatocyte degeneration, and injury in mice with nonalcoholic fatty liver disease
title_full_unstemmed Pachymaran alleviates fat accumulation, hepatocyte degeneration, and injury in mice with nonalcoholic fatty liver disease
title_short Pachymaran alleviates fat accumulation, hepatocyte degeneration, and injury in mice with nonalcoholic fatty liver disease
title_sort pachymaran alleviates fat accumulation hepatocyte degeneration and injury in mice with nonalcoholic fatty liver disease
topic pachymaran
nonalcoholic fatty liver disease
adenylate-activated protein kinase
liver
fat
url https://doi.org/10.1515/med-2025-1241
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AT wanmin pachymaranalleviatesfataccumulationhepatocytedegenerationandinjuryinmicewithnonalcoholicfattyliverdisease
AT lihong pachymaranalleviatesfataccumulationhepatocytedegenerationandinjuryinmicewithnonalcoholicfattyliverdisease
AT liuxing pachymaranalleviatesfataccumulationhepatocytedegenerationandinjuryinmicewithnonalcoholicfattyliverdisease