Metabolic Syndrome and Associated Risk Factors in Norwegian Trauma-Exposed Inpatients: A Cross-Sectional Comparison with Blood Donors
Grethe Emilie Roer,1,2 Ingeborg Bolstad,3 Dawit Shawel Abebe,1,2 Jan Aaseth,3,4 Morten Haugen,5,6 Lars Lien1,3 1Research Center for Substance Use Disorders and Mental Illness, Innlandet Hospital Trust, Brumunddal, NO-2381, Norway; 2Department of Nursing and Health Promotion, Oslo Metropolitan Univer...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2025-08-01
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| Series: | Diabetes, Metabolic Syndrome and Obesity |
| Subjects: | |
| Online Access: | https://www.dovepress.com/metabolic-syndrome-and-associated-risk-factors-in-norwegian-trauma-exp-peer-reviewed-fulltext-article-DMSO |
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| Summary: | Grethe Emilie Roer,1,2 Ingeborg Bolstad,3 Dawit Shawel Abebe,1,2 Jan Aaseth,3,4 Morten Haugen,5,6 Lars Lien1,3 1Research Center for Substance Use Disorders and Mental Illness, Innlandet Hospital Trust, Brumunddal, NO-2381, Norway; 2Department of Nursing and Health Promotion, Oslo Metropolitan University, Oslo, NO-0130, Norway; 3Faculty of Social and Health Sciences, University of Inland Norway, Elverum, NO-2418, Norway; 4Research Department, Innlandet Hospital Trust, Brumunddal, NO-2381, Norway; 5Department of Blood Centre and Laboratory Medicine, Innlandet Hospital Trust, Brumunddal, NO-2381, Norway; 6Faculty of Medicine, University of Oslo, Blindern, Oslo, NO-0316, NorwayCorrespondence: Grethe Emilie Roer, Research Center for Substance Use Disorders and Mental Illness, Innlandet Hospital Trust, P. O. Box 104, Brumunddal, N-2381, Norway, Email grethe.emilie.roer@sykehuset-innlandet.noPurpose: The incidence of metabolic syndrome (MetS) is increasing, and research indicates a further increased risk of MetS in trauma-exposed individuals, which is yet to be fully understood. Therefore, this study aimed to investigate the risk of MetS in trauma-exposed inpatients compared to blood donors and the influence of putative associated psychological, biological, and behavioral risk factors for MetS.Patients and Methods: A cross-sectional study of trauma-exposed inpatients (n = 134) compared to blood donors (n = 68) was conducted. Clinical data, blood biomarkers, and self-administered questionnaires were collected. Descriptive statistics and multivariable logistic regression, including interaction analyses, were performed to explore the odds ratio (OR) of MetS among trauma-exposed inpatients compared to blood donors as well as the interaction effects of putative risk factors.Results: A significantly higher age- and gender adjusted OR (OR = 2.51, 95% CI 1.18– 5.34) of MetS was found among trauma-exposed inpatients compared to the blood donors. Adjusted for education, cigarette smoking, symptoms of disordered eating and consumption of selected nutrients, the higher OR of MetS remained significant in the inpatients compared to the blood donors, ranging from OR = 2.27 95% CI 1.00– 5.14 for symptoms of “dieting” to OR = 3.06 95% CI 1.16– 8.10 for adult trauma. A significant interaction effect was documented only between group and age (OR = 1.07, 95% CI 1.01– 1.13).Conclusion: The trauma-exposed inpatients in this study had significantly higher age- and gender adjusted risk of MetS compared to the blood donors, and psychological and behavioral lifestyle factors appeared to increase the risk of MetS.Keywords: insulin resistance, metabolism, type 2 diabetes mellitus, mental disorders, posttraumatic stress, disordered eating |
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| ISSN: | 1178-7007 |