Inhibition of MAPK and STAT3-SOCS3 by Sakuranetin Attenuated Chronic Allergic Airway Inflammation in Mice

Inhibition of MAPK and STAT3-SOCS3 by Sakuranetin Attenuated Chronic Allergic Airway Inflammation in Mice

Asthma allergic disease is caused by airway chronic inflammation. Some intracellular signaling pathways, such as MAPK and STAT3-SOCS3, are involved in the control of airway inflammation in asthma. The flavonoid sakuranetin demonstrated an anti-inflammatory effect in different asthma models. Our aim...

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Main Authors: Fernanda P. R. Santana, Rafael C. da Silva, Simone dos S. Grecco, Aruanã J. M. C. R. Pinheiro, Luciana C. Caperuto, Fernanda M. Arantes-Costa, Samuel R. Claudio, Kelly Yoshizaki, Mariângela Macchione, Daniel A. Ribeiro, Iolanda F. L. C. Tibério, Lídio G. Lima-Neto, João H. G. Lago, Carla M. Prado
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2019/1356356
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http://dx.doi.org/10.1155/2019/1356356

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