Synthesis, Characterization and Antimicrobial Properties of Schiff Bases Derived from Condensation of 8-Formyl-7-hydroxy-4-methylcoumarin and Substituted Triazole Derivatives
Two biologically active classes of compounds coumarins and triazoles were employed to form the Schiff bases. The synthesized Schiff base viz., 3-aryl-[(1-isocyano-4-methyl-7-hydroxycoumarin)]-5-methyl-1,3,4-triazoline-2-one and its substituents were obtained by the condensation of amino group of mon...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2009/787150 |
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| author | Kumar Sanjeev S. Lamani Oblennavar Kotresh Mohammed Shafi A. Phaniband Jagannath C. Kadakol |
| author_facet | Kumar Sanjeev S. Lamani Oblennavar Kotresh Mohammed Shafi A. Phaniband Jagannath C. Kadakol |
| author_sort | Kumar Sanjeev S. Lamani |
| collection | DOAJ |
| description | Two biologically active classes of compounds coumarins and triazoles were employed to form the Schiff bases. The synthesized Schiff base viz., 3-aryl-[(1-isocyano-4-methyl-7-hydroxycoumarin)]-5-methyl-1,3,4-triazoline-2-one and its substituents were obtained by the condensation of amino group of mono and disubstituted derivatives of 3-methyl-5-oxo-1,2, 4-triazoles with 8-formyl-7-hydroxy-4-methylcoumarin in alcohol. The characterization were studied by elemental analysis, IR, 1H NMR and mass spectra. The biological activities of the compounds were assayed against two bacterial via, B. subtilis, E.coli and two fungal strains A. niger, C.albican. The results indicate that the present compounds may serve as better fungicides when compared to bactericides. The synthesized compounds have turned to be wonder compounds possessing antimicrobial properties. |
| format | Article |
| id | doaj-art-d2b5eb9124f245e1825bdd073d7f55ad |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-d2b5eb9124f245e1825bdd073d7f55ad2025-08-20T03:24:07ZengWileyE-Journal of Chemistry0973-49452090-98102009-01-016S1S239S24610.1155/2009/787150Synthesis, Characterization and Antimicrobial Properties of Schiff Bases Derived from Condensation of 8-Formyl-7-hydroxy-4-methylcoumarin and Substituted Triazole DerivativesKumar Sanjeev S. Lamani0Oblennavar Kotresh1Mohammed Shafi A. Phaniband2Jagannath C. Kadakol3Department of Chemistry, Karnataka Unversity’s Karnatak Science College, Dharwad-580001, Karnataka, IndiaDepartment of Chemistry, Karnataka Unversity’s Karnatak Science College, Dharwad-580001, Karnataka, IndiaDepartment of Chemistry, Karnataka Unversity’s Karnatak Science College, Dharwad-580001, Karnataka, IndiaDepartment of Chemistry, Karnataka Unversity’s Karnatak Science College, Dharwad-580001, Karnataka, IndiaTwo biologically active classes of compounds coumarins and triazoles were employed to form the Schiff bases. The synthesized Schiff base viz., 3-aryl-[(1-isocyano-4-methyl-7-hydroxycoumarin)]-5-methyl-1,3,4-triazoline-2-one and its substituents were obtained by the condensation of amino group of mono and disubstituted derivatives of 3-methyl-5-oxo-1,2, 4-triazoles with 8-formyl-7-hydroxy-4-methylcoumarin in alcohol. The characterization were studied by elemental analysis, IR, 1H NMR and mass spectra. The biological activities of the compounds were assayed against two bacterial via, B. subtilis, E.coli and two fungal strains A. niger, C.albican. The results indicate that the present compounds may serve as better fungicides when compared to bactericides. The synthesized compounds have turned to be wonder compounds possessing antimicrobial properties.http://dx.doi.org/10.1155/2009/787150 |
| spellingShingle | Kumar Sanjeev S. Lamani Oblennavar Kotresh Mohammed Shafi A. Phaniband Jagannath C. Kadakol Synthesis, Characterization and Antimicrobial Properties of Schiff Bases Derived from Condensation of 8-Formyl-7-hydroxy-4-methylcoumarin and Substituted Triazole Derivatives E-Journal of Chemistry |
| title | Synthesis, Characterization and Antimicrobial Properties of Schiff Bases Derived from Condensation of 8-Formyl-7-hydroxy-4-methylcoumarin and Substituted Triazole Derivatives |
| title_full | Synthesis, Characterization and Antimicrobial Properties of Schiff Bases Derived from Condensation of 8-Formyl-7-hydroxy-4-methylcoumarin and Substituted Triazole Derivatives |
| title_fullStr | Synthesis, Characterization and Antimicrobial Properties of Schiff Bases Derived from Condensation of 8-Formyl-7-hydroxy-4-methylcoumarin and Substituted Triazole Derivatives |
| title_full_unstemmed | Synthesis, Characterization and Antimicrobial Properties of Schiff Bases Derived from Condensation of 8-Formyl-7-hydroxy-4-methylcoumarin and Substituted Triazole Derivatives |
| title_short | Synthesis, Characterization and Antimicrobial Properties of Schiff Bases Derived from Condensation of 8-Formyl-7-hydroxy-4-methylcoumarin and Substituted Triazole Derivatives |
| title_sort | synthesis characterization and antimicrobial properties of schiff bases derived from condensation of 8 formyl 7 hydroxy 4 methylcoumarin and substituted triazole derivatives |
| url | http://dx.doi.org/10.1155/2009/787150 |
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