GNA15 predicts poor outcomes as a novel biomarker related to M2 macrophage infiltration in ovarian cancer

GNA15 predicts poor outcomes as a novel biomarker related to M2 macrophage infiltration in ovarian cancer

BackgroundThe exploration of genetic signatures within the ovarian cancer (OC) tumor microenvironment (TME) remains limited. M2-like tumor-associated macrophages (M2-like TAMs) are pivotal in OC progression and therapy. This study aims to establish a novel prognostic signature and identify M2-like T...

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Bibliographic Details
Main Authors: Qin Liu, Yabing Sun, Tao Zhang, Wanrun Lin, Jing Zhang, Huijuan Zhang, Wenxin Zheng, Hong Xu, Feng Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
ovarian carcinoma
cancer microenvironment
tumor-associated macrophages
prognostic model
GNA15
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1512086/full
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