Intravitreal Injections for Macular Edema in Silicone Oil Filled Eyes
Khaled Safadi, Yossi Eshel, Jaime Levy, Liran Tiosano, Tareq Jaouni, Samer Khateb Department of Ophthalmology, Hadassah University Medical Center, Faculty of Medicine, the Hebrew University of Jerusalem, Jerusalem, IsraelCorrespondence: Samer Khateb, Department of Ophthalmology, Hadassah University...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2024-11-01
|
| Series: | Clinical Ophthalmology |
| Subjects: | |
| Online Access: | https://www.dovepress.com/intravitreal-injections-for-macular-edema-in-silicone-oil-filled-eyes-peer-reviewed-fulltext-article-OPTH |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850162730675208192 |
|---|---|
| author | Safadi K Eshel Y Levy J Tiosano L Jaouni T Khateb S |
| author_facet | Safadi K Eshel Y Levy J Tiosano L Jaouni T Khateb S |
| author_sort | Safadi K |
| collection | DOAJ |
| description | Khaled Safadi, Yossi Eshel, Jaime Levy, Liran Tiosano, Tareq Jaouni, Samer Khateb Department of Ophthalmology, Hadassah University Medical Center, Faculty of Medicine, the Hebrew University of Jerusalem, Jerusalem, IsraelCorrespondence: Samer Khateb, Department of Ophthalmology, Hadassah University Medical Center, Faculty of Medicine, the Hebrew University of Jerusalem, Jerusalem, 91120, Israel, Email Samer.khateb@mail.huji.ac.ilPurpose: Macular edema is a known complication following complicated retinal detachment repair with silicone oil (SiO) tamponade. Limited previous research has not led to a consensus regarding the safety and efficacy of intra-SiO injections. Consequently, we aim to present our case series study on intra-SiO injections for postoperative macular edema.Methods: A retrospective, single-center, case series study of eight eyes that developed macular edema postoperatively following complicated retinal detachment repair surgery with SiO tamponade, were treated with different forms of intravitreal injections such as steroids or anti-vascular endothelial growth factor (VEGF). The main outcome measures included visual acuity (VA), central subfield macular thickness (CSMT), and the type and number of injections.Results: The mean age (±SD) of the patients was 64.75± 8.9 years. The mean follow-up period (±SD) was 3.1± 2.2 years. The mean (±SD) number of injections was 8.25± 7.24. Mean (±SD) VA (in LogMAR) and CSMT before injections were 1.7± 0.8 and 488± 104 μm, respectively. At the last follow-up visit, the mean (±SD) VA and CSMT were 1.4± 0.7 (p-value=0.45) and 396± 184 μm (p-value=0.11), respectively. Overall, patients showed a partial response without a significant worsening of the macular edema and VA. No complications were reported following repetitive intravitreal injections.Conclusion: Macular edema in silicone oil-filled eyes may be safely and effectively treated with intravitreal injections to halt its deterioration and preserve vision, especially when SiO removal is not anticipated in the foreseeable future.Keywords: intravitreal injections, silicone oil, retinal detachment, Retina, optical coherence tomography, OCT, macular edema, cystoid macular edema, CME |
| format | Article |
| id | doaj-art-d2aafc2291ce48a9900969e8316fc785 |
| institution | OA Journals |
| issn | 1177-5483 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj-art-d2aafc2291ce48a9900969e8316fc7852025-08-20T02:22:29ZengDove Medical PressClinical Ophthalmology1177-54832024-11-01Volume 183405341697587Intravitreal Injections for Macular Edema in Silicone Oil Filled EyesSafadi KEshel YLevy JTiosano LJaouni TKhateb SKhaled Safadi, Yossi Eshel, Jaime Levy, Liran Tiosano, Tareq Jaouni, Samer Khateb Department of Ophthalmology, Hadassah University Medical Center, Faculty of Medicine, the Hebrew University of Jerusalem, Jerusalem, IsraelCorrespondence: Samer Khateb, Department of Ophthalmology, Hadassah University Medical Center, Faculty of Medicine, the Hebrew University of Jerusalem, Jerusalem, 91120, Israel, Email Samer.khateb@mail.huji.ac.ilPurpose: Macular edema is a known complication following complicated retinal detachment repair with silicone oil (SiO) tamponade. Limited previous research has not led to a consensus regarding the safety and efficacy of intra-SiO injections. Consequently, we aim to present our case series study on intra-SiO injections for postoperative macular edema.Methods: A retrospective, single-center, case series study of eight eyes that developed macular edema postoperatively following complicated retinal detachment repair surgery with SiO tamponade, were treated with different forms of intravitreal injections such as steroids or anti-vascular endothelial growth factor (VEGF). The main outcome measures included visual acuity (VA), central subfield macular thickness (CSMT), and the type and number of injections.Results: The mean age (±SD) of the patients was 64.75± 8.9 years. The mean follow-up period (±SD) was 3.1± 2.2 years. The mean (±SD) number of injections was 8.25± 7.24. Mean (±SD) VA (in LogMAR) and CSMT before injections were 1.7± 0.8 and 488± 104 μm, respectively. At the last follow-up visit, the mean (±SD) VA and CSMT were 1.4± 0.7 (p-value=0.45) and 396± 184 μm (p-value=0.11), respectively. Overall, patients showed a partial response without a significant worsening of the macular edema and VA. No complications were reported following repetitive intravitreal injections.Conclusion: Macular edema in silicone oil-filled eyes may be safely and effectively treated with intravitreal injections to halt its deterioration and preserve vision, especially when SiO removal is not anticipated in the foreseeable future.Keywords: intravitreal injections, silicone oil, retinal detachment, Retina, optical coherence tomography, OCT, macular edema, cystoid macular edema, CMEhttps://www.dovepress.com/intravitreal-injections-for-macular-edema-in-silicone-oil-filled-eyes-peer-reviewed-fulltext-article-OPTHintravitreal injectionssilicone oilretinal detachmentretinaoptical coherence tomographyoctmacular edemacystoid macular edemacme. |
| spellingShingle | Safadi K Eshel Y Levy J Tiosano L Jaouni T Khateb S Intravitreal Injections for Macular Edema in Silicone Oil Filled Eyes Clinical Ophthalmology intravitreal injections silicone oil retinal detachment retina optical coherence tomography oct macular edema cystoid macular edema cme. |
| title | Intravitreal Injections for Macular Edema in Silicone Oil Filled Eyes |
| title_full | Intravitreal Injections for Macular Edema in Silicone Oil Filled Eyes |
| title_fullStr | Intravitreal Injections for Macular Edema in Silicone Oil Filled Eyes |
| title_full_unstemmed | Intravitreal Injections for Macular Edema in Silicone Oil Filled Eyes |
| title_short | Intravitreal Injections for Macular Edema in Silicone Oil Filled Eyes |
| title_sort | intravitreal injections for macular edema in silicone oil filled eyes |
| topic | intravitreal injections silicone oil retinal detachment retina optical coherence tomography oct macular edema cystoid macular edema cme. |
| url | https://www.dovepress.com/intravitreal-injections-for-macular-edema-in-silicone-oil-filled-eyes-peer-reviewed-fulltext-article-OPTH |
| work_keys_str_mv | AT safadik intravitrealinjectionsformacularedemainsiliconeoilfilledeyes AT eshely intravitrealinjectionsformacularedemainsiliconeoilfilledeyes AT levyj intravitrealinjectionsformacularedemainsiliconeoilfilledeyes AT tiosanol intravitrealinjectionsformacularedemainsiliconeoilfilledeyes AT jaounit intravitrealinjectionsformacularedemainsiliconeoilfilledeyes AT khatebs intravitrealinjectionsformacularedemainsiliconeoilfilledeyes |