Pyoderma Gangrenosum with Neurofibromatosis: Understanding a Possible Relationship and Identifying Risk with Immunosuppressants

Association of Pyoderma Gangrenosum with Neurofibromatosis is extremely rare; only one case has been reported so far. We present one such patient, who also developed bone marrow suppression after treatment with Azathioprine, and reported an acute onset of Telogen Effluvium. The rare association...

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Main Authors: Mihika Noronha, Vijay Aithal
Format: Article
Language:English
Published: Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON) 2023-10-01
Series:Nepal Journal of Dermatology, Venereology & Leprology
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Online Access:https://www.nepjol.info/index.php/NJDVL/article/view/56528
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author Mihika Noronha
Vijay Aithal
author_facet Mihika Noronha
Vijay Aithal
author_sort Mihika Noronha
collection DOAJ
description Association of Pyoderma Gangrenosum with Neurofibromatosis is extremely rare; only one case has been reported so far. We present one such patient, who also developed bone marrow suppression after treatment with Azathioprine, and reported an acute onset of Telogen Effluvium. The rare association of these two seemingly unrelated conditions and the need to be vigilant about the possibility of myelosuppression with azathioprine presenting as sudden onset, severe alopecia is highlighted.
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institution Kabale University
issn 2091-0231
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language English
publishDate 2023-10-01
publisher Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)
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series Nepal Journal of Dermatology, Venereology & Leprology
spelling doaj-art-d2a9f10003134bf5b4b07fb26e35bd9c2025-08-23T10:03:42ZengSociety of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)Nepal Journal of Dermatology, Venereology & Leprology2091-02312091-167X2023-10-0121210.3126/njdvl.v21i2.56528Pyoderma Gangrenosum with Neurofibromatosis: Understanding a Possible Relationship and Identifying Risk with ImmunosuppressantsMihika Noronha0Vijay Aithal1https://orcid.org/0000-0002-7998-4959St. John’s Medical College, Bangalore, IndiaSt John's Medical College, Bangalore, India Association of Pyoderma Gangrenosum with Neurofibromatosis is extremely rare; only one case has been reported so far. We present one such patient, who also developed bone marrow suppression after treatment with Azathioprine, and reported an acute onset of Telogen Effluvium. The rare association of these two seemingly unrelated conditions and the need to be vigilant about the possibility of myelosuppression with azathioprine presenting as sudden onset, severe alopecia is highlighted. https://www.nepjol.info/index.php/NJDVL/article/view/56528AzathioprineNeurofibromatosisPyoderma GangrenosumTelogen effluvium
spellingShingle Mihika Noronha
Vijay Aithal
Pyoderma Gangrenosum with Neurofibromatosis: Understanding a Possible Relationship and Identifying Risk with Immunosuppressants
Nepal Journal of Dermatology, Venereology & Leprology
Azathioprine
Neurofibromatosis
Pyoderma Gangrenosum
Telogen effluvium
title Pyoderma Gangrenosum with Neurofibromatosis: Understanding a Possible Relationship and Identifying Risk with Immunosuppressants
title_full Pyoderma Gangrenosum with Neurofibromatosis: Understanding a Possible Relationship and Identifying Risk with Immunosuppressants
title_fullStr Pyoderma Gangrenosum with Neurofibromatosis: Understanding a Possible Relationship and Identifying Risk with Immunosuppressants
title_full_unstemmed Pyoderma Gangrenosum with Neurofibromatosis: Understanding a Possible Relationship and Identifying Risk with Immunosuppressants
title_short Pyoderma Gangrenosum with Neurofibromatosis: Understanding a Possible Relationship and Identifying Risk with Immunosuppressants
title_sort pyoderma gangrenosum with neurofibromatosis understanding a possible relationship and identifying risk with immunosuppressants
topic Azathioprine
Neurofibromatosis
Pyoderma Gangrenosum
Telogen effluvium
url https://www.nepjol.info/index.php/NJDVL/article/view/56528
work_keys_str_mv AT mihikanoronha pyodermagangrenosumwithneurofibromatosisunderstandingapossiblerelationshipandidentifyingriskwithimmunosuppressants
AT vijayaithal pyodermagangrenosumwithneurofibromatosisunderstandingapossiblerelationshipandidentifyingriskwithimmunosuppressants